Situs inversus may be associated with other congenital anomalies such as duodenal atresia, asplenism
, multiple spleens, ectopic kidney, horseshoe kidney and various pulmonary and vascular abnormalities.
Other risk factors include smoking, asplenism
, specific genetic predisposition, certain immunodeficiency disorders, and chronic lung diseases such as chronic obstructive pulmonary disease and bronchiectasis [2, 5].
Due to the repeated infarctions an asplenism
develops in early years of life.
Comorbidities that predispose patients to complications or more severe illness should also be taken under consideration and include COPD, diabetes, immunosuppressive therapies and conditions, liver or kidney disease, asplenism
, and alcoholism.
Background Influenza vaccine is of proven benefit and recommended annually for those with chronic cardiovascular or pulmonary diseases, diabetes, renal failure, functional asplenism
, residents of nursing homes, adults over the age of 65, and health care personnel.
Eventually, a functional and anatomic asplenism
develop due to the decreased antibody production, opsonization, and reticuloendothelial functions.
Monitoring can help prevent illness associ-ated with delayed diagnosis of additional autoim-mune diseases such as Addison's disease and hypo-parathyroidism, as well as oral cancer, which may develop if candidiasis is not treated aggressively, and infection due to asplenism
, which is present in a sub-group of patients.9 Our patient was diagnosed PGA I because this manifestations: hypoparathyroid, chronic mucocutaneous candidiasis.