aspartate transaminase

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aspartate transaminase

 (AST) (ASAT) [ah-spahr´tāt trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from aspartate to α-ketoglutarate to form glutamate and oxaloacetate, requiring the coenzyme pyridoxal phosphate; it is normally present in serum and in various body tissues, especially in the heart and liver. (See accompanying table.) It is released into the serum as the result of tissue injury, especially injury to the heart or liver, hence the concentration in the serum may be increased in myocardial infarction or acute damage to hepatic cells. Serum levels are also increased in some muscle diseases, such as progressive muscular dystrophy. Called also glutamic-oxaloacetic transaminase.

as·par·tate a·mi·no·trans·fer·ase (AST),

an enzyme catalyzing the reversible transfer of an amine group from l-glutamate to oxaloacetate, forming α-ketoglutarate and l-aspartate; an aid in diagnosing viral hepatitis and myocardial infarction.

aspartate transaminase

/as·par·tate trans·am·i·nase/ (AST) (ASAT) (trans-am´ĭ-nās) an enzyme normally present in body tissues, especially in the heart and liver; it is released into the serum as the result of tissue injury, hence the concentration in the serum (SGOT) may be increased in disorders such as myocardial infarction or acute damage to hepatic cells.

aspartate transaminase


Asp; any salt of aspartic acid; aspartic acid in dissociated form.

aspartate carbamoyl transferase
enzyme catalyzing the condensation of carbamoyl phosphate and l-aspartate to N-carbamoyl-l-aspartate. A regulatory, allosteric enzyme in the synthesis of pyrimidine nucleotides.
aspartate transaminase

Patient discussion about aspartate transaminase

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References in periodicals archive ?
Blood samples for measuring serum alanine amino transferase (ALT), aspartate amino transferase (AST) and alkaline phosphatase (ALP) along with liver samples for hepatic histological examination were taken after 24 hours of last dose.
Liver enzymes: AlanineAmino Transferase (ALT), Aspartate Amino Transferase (AST), Gamma-Glutamyl-Transferase (GGT) and Alkaline Phosphatase (ALP) were measured by Vitros 350 autoanalyser (New York, USA; Product code 680-2153) using their accompanying commercial kits (Vitros Chemistry Products, Ortho-Clinical Diagnostics, Johnson-Johnson Company, New York, USA).
Aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) were determined by the method of Duncan et al.
Plasma total proteins (g/dL), creatinine (mg/dL), blood urea nitrogen (mg/dL), plasma glucose (mg/dL), triglycerides (mg/dL), albumin (g/dL), alanine amino transferase (ALT; IU/L), and aspartate amino transferase (AST; IU/L) activities were analyzed using available kits supplied by Bio Merieux SA, F-69280 Marcy l'Etoile, France.
In this study, the rates of cirrhosis were calculated from National Health and Nutrition Examination Survey (NHANES) data by using two surrogate indicators, the aspartate amino transferase to platelet ratio index (APRI) and the FIB-4 score.
9 mg%), alanine amino transferase being 52 IU/L, aspartate amino transferase being 1045 IU/L, and alkaline phosphatase being 203 IU/L.
9mg/dl, an alanine amino transferase level of 250 U/l, an aspartate amino transferase level of 46 U/l, a total bilirubin level of 1.
Biochemical analysis in the serum of TAA-treated rats revealed a significant increase in the levels of tumor necrosis factor (TNF-a) and transforming growth factor (TGF-AY), as well as, the activities of aspartate amino transferase (AST), alanine aminotransferase (ALT) and gamma glutamyl transferase (GGT).
Table 1: Blood chemistry and Hematological findings Variable(Unit)(normal range) Value First admission Aspartate amino transferase (U/L)(2-31) 20 Alonine minotransferase (U/L)(2-31) 9 Alkaline phoshatase(U/L)(46-306) 245 Billirubin Total (mg%) (0.
8 minutes aspartate amino transferase (AST): 126 U/L (normal: 0-35) alanine amino transferase (ALT): 102 U/L (normal:0-45) albumin: 2.
The serum separated was used for assay of Alanine amino transferase (ALT), Aspartate amino transferase (AST), alkaline phosphatase (ALP), albumin, triglycerides and serum bilirubin according to the instructions provided by the company.
aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), total protein, albumin, globulin and serum bilirubin as per the spectrophotometric methods supplied by 'SPAN' diagnostic kits.