The enlargement of the thyroid gland (goitre) in Hashimoto's thyroiditis (HT) is due to the lymphocytic infiltration, presence of oncocytes, previously named Hurthle cells, Askanazy
cells or oxyphyllic cells, and fibrosis, that increases in the final atrophic stage of the disease (2).
Professor Max Askanazy
(1865-1940): from Konigsberg (Prussia) to Geneva.
In 1903 Max Askanazy
, a pathologist in Geneva, discovered a parathyroid tumour at the post mortem of a patient with this disease, (also called Von Recklinghausen's disease of bone), but, interestingly enough, he made no association between the two.
Jentzer and Askanazy
first coined the term neurotropism to describe this process.
(15) says that the localization of the amyloid depends partly on the kind and intensity of the function of an organ.