Hysteroscopic treatment of severe
Asherman's syndrome and subsequent fertility.
Abbott, "Use of a Hysteroscopic Morcellator to Resect Miscarriage in a Woman With Recurrent
Asherman's Syndrome," Journal of Minimally Invasive Gynecology, vol.
Taylor, "Bone marrow-derived stem cell (BMDSC) transplantation improves fertility in a murine model of
Asherman's syndrome," PLoS One, vol.
Factors affecting reproductive outcome of hysteroscopic adhesiolysis for
Asherman's syndrome. Fertil Steril 2008 Mar; 89(3):715-722.
Gargett, "Regenerating endometrium from stem/progenitor cells: is it abnormal in endometriosis,
Asherman's syndrome and infertility?" Current Opinion in Obstetrics and Gynecology, vol.
(9) also evaluated the rabbit as an experimental model of
Asherman's syndrome and tried to induce synechiae using traumatic curettage as a trigger mechanism.
Patients with
Asherman's syndrome and cervical stenosis are most at risk.
Defects of the outflow tract (
Asherman's Syndrome or Intrauterine adhesions) -- excluded by positive progesterone challenge test.
SAN FRANCISCO --
Asherman's syndrome is a straightforward diagnosis in patients with secondary amenorrhea.
Asherman's syndrome is defined as partial or complete obstruction of the uterine cavity due to damage to the basal layer of the endometrium [1, 2] and is primarily caused by intrauterine procedures and infections often associated with miscarriage or curettage for postpartum placental retention [1].
Differential diagnosis of such unusual findings includes intrauterine devices (IUD),
Asherman's syndrome, calcified submucous fibroids, foreign bodies and mixed mesodermal tumours.
Joseph Asherman defined
Asherman's syndrome in 1948 as a case of severe intrauterine adhesions secondary to trauma to gravid uterus.