Aschoff nodule


Also found in: Encyclopedia.

Aschoff body

A small granulomatous lesion composed of macrophages, lymphocytes and multinucleated giant cells, which surrounds pale eosinophilic collagenous material, classically seen in rheumatic fever-related myocarditis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Aschoff nodule

A small nodule composed of cells and leukocytes found in the interstitial tissues of the heart in rheumatic myocarditis.
See also: Aschoff, Ludwig
Medical Dictionary, © 2009 Farlex and Partners

Aschoff nodule

A specific microscopic sign of RHEUMATIC FEVER. An area of dead tissue (necrosis) is surrounded by lymphocytes, scavenging cells (histiocytes) and giant cells. (Karl Albert Ludwig Aschoff, German pathologist, 1866–1942).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005