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A major constituent of oil of chenopodium; an anthelmintic.
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As an ultimate demonstration, they succeeded in having the reactor actually produce two types of medicine, the antimalarial artemisinin and the antiparasitic drug ascaridole. In the magazine Angewandte Chemie, they describe how this reactor can be easily scaled up, can be used for a wide range of chemical reactions and maintains stable production under changing weather conditions.
and its constituents ascaridole and isoascaridole had [LC.sub.50] values of only 2.12, 0.86, and 2.16 [micro]g [g.sup.-1] insect weight, respectively, in adult S.
(2006) described that boldo leaves contain tannins, essential oils (mainly ascaridole and cineole), and flavonoids, of which catechin was recently reported to be the most abundant of the metabolites.
Activation of the endoperoxide ascaridole modulates its sensitizing capacity.
Combined analysis of the essential oil of Chenopodium ambrosioides by GC, GCMS and 13C-RMN spectroscopy: quantitative determination of ascaridole, a heatsensitive compound.
Abbreviations: Asc, ascaridole; Car, carvacrol; Caryo, caryophyllene oxide; DMSO, dimethyl sulfoxide; EO, essential oil; GTM, glucantime; HRGC-MS, high resolution gas chromatography-mass spectrometry; p.i., post-infection.
ambrosioides is unknown, but some authors have hypothesized that ascaridole (endoperoxide), an active molecule, generates free radicals that act on parasitic DNA [43].