Refined human artificial chromosome
vectors for gene therapy and animal transgenesis.
Kouprina said that conventional gene therapy uses vectors like viruses to insert genes into chromosomes, which can cause problems which do not happen with human artificial chromosomes
because they do not interfere with other parts of the genome.
The construction of bacterial artificial chromosome
(BAC) libraries, p.
* Chromos Molecular Systems, founded in 1996 and located in British Columbia, is developing what could be the most powerful genetic engineering technology to date: artificial chromosomes
, which would enable the engineering of multiple, complex human traits.
The program for the evening was entitled 'Artificial Chromosomes
and Plant Toxins as Therapeutic Agents'.
The task of creating such herds may be made much easier by the artificial chromosomes
developed by Chromos Molecular Systems, near Vancouver, BC.
SCIENTISTS at the Medical Research Council in Edinburgh have developed artificial chromosomes
to help combat the defective genes which cause illnesses such as cystic fibrosis and haemophilia.
A DNA contig of this region spanning 2,400 kb was constructed from large-capacity yeast artificial chromosomes
and P1 bacteriophage clones (76).
The technique, developed by a team at the University of California, San Diego, uses bacterial artificial chromosomes
(BACs) to insert defective copies of genes into stem cells.
Laboratory techniques and applications for researchers investigating the identification and function of genes relevant to normal physiology and cancer are described by specialists in specific aspects of gene identification and full-length gene cloning, gene profiling, the chromatin modification of gene regulation, bacterial artificial chromosomes
, cancer cytogenetic analysis, and other topics.
Comparative sequence analysis of colinear barley and rice bacterial artificial chromosomes
. Plant Physiol.
Metaphase and interphase fluorescence in situ hybridization mapping of the rice genome with bacterial artificial chromosomes