Argentine hemorrhagic fever


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A viral illness caused by the Junin arenavirus, named in 1953 after its city of isolation
Epidemiology Transmitted by contact with rodent urine; 23 outbreaks have been recorded in the maize-producing region of Argentina
Rodent vectors Akodon arenicola, Calomys laucha, C musculinus
Management Rehydration; high—15–45%—mortality may decrease to 1–4% with convalescent serum-specific Junin virus immune plasma

Argentine hemorrhagic fever

A viral illness caused by the Junin arenavirus Epidemiology Transmitted by contact with rodent urine; 23 outbreaks have been recorded, in the maize-producing region of Argentina Rodent vectors Akodon arenicola, Calomys laucha, C musculinus Clinical 1-2 wk incubation, followed by mucocutaneous hemorrhage, fever, anorexia, N&V, fluid loss and oliguria, hypotension, shock, severe myalgia, leukopenia, thrombocytopenia, transient hypocomplementemia Management Rehydration; high–15-45% mortality may ↓ to 1-4% with convalescent serum-
specific Junin virus immune plasma