area under the curve


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area

 [a´re-ah] (pl. a´reae, areas) (L.)
a limited space or plane surface.
acoustic a's auditory areas.
association a's areas of the cerebral cortex (excluding primary areas) connected with each other and with the neothalamus; they are responsible for higher mental and emotional processes, including memory, learning, speech, and the interpretation of sensations.
Area. Functional areas and lobes of the cerebrum.
auditory a's two contiguous areas of the temporal lobe in the region of the anterior transverse temporal gyrus, known as the primary and secondary auditory areas. Called also acoustic areas.
Broca's motor speech area an area comprising parts of the opercular and triangular portions of the inferior frontal gyrus; injury to this area may result in motor aphasia.
Broca's parolfactory area a small area of cortex on the medial surface of each cerebral hemisphere, between the anterior and posterior parolfactory sulci. Called also area subcallosa.
Brodmann's a's specific occipital and preoccipital areas of the cerebral cortex, distinguished by differences in the arrangement of their six cellular layers, and identified by numbering each area. They are considered to be the seat of specific functions of the brain.
catchment area
1. the geographical region drained by one body of water.
2. the area whose residents are served by a specialized health care agency. Called also catchment.
contact area proximal surface.
embryonic area (germinal area) (area germinati´va) embryonic disk.
Kiesselbach's area an area on the anterior part of the nasal septum, richly supplied with capillaries, and a common site of epistaxis (nosebleed).
language area any nerve center of the cerebral cortex, usually in the dominant hemisphere, controlling the understanding or use of language.
motor area any area of the cerebral cortex primarily involved in stimulating muscle contractions; most are in the precentral gyri. See also premotor area, sensorimotor area, and Broca's motor speech area.
motor speech area see Broca's motor speech area and Wernicke's area.
occupational performance a's categories of activities that make up an individual's occupational performance; they include activities of daily living, work activities, and play or leisure activities. A delay in any of these areas may be addressed by occupational therapy intervention.
olfactory area
1. a general area of the brain, including the olfactory bulb, tract, and trigone, the anterior portion of the gyrus cinguli, and the uncus.
postcentral area (postrolandic area) an area just posterior to the central sulcus of the cerebral hemisphere that is the primary receiving area for general sensations.
precentral area primary somatomotor area.
premotor area an area of the motor cortex of the frontal lobe immediately in front of the precentral gyrus.
primary area areas of the cerebral cortex comprising the motor and sensory regions.
primary receiving a's the areas of the cerebral cortex that receive the thalamic projections of the primary sensory modalities such as vision, hearing, and smell. Called also sensory areas.
primary somatomotor area an area in the posterior part of the frontal lobe just anterior to the central sulcus; different regions control motor activity of specific parts of the body. Called also precentral area and rolandic area.
projection a's those areas of the cerebral cortex that receive the most direct projection of the sensory systems of the body.
sensorimotor area the cortex of the precentral and postcentral gyri, which are the motor area and the primary receiving area for general sensations, respectively.
sensory a's primary receiving areas.
sensory association area an association area around the borders of a primary receiving area, where sensory stimuli are interpreted.
silent area an area of the brain in which pathologic conditions may occur without producing symptoms.
somatic sensory area (somatosensory area) either of two cortical projection areas in or near the postcentral gyrus where conscious perception of somatic sensations occurs, known as the first or primary somatosensory area and the second or secondary somatosensory area.
area subcallo´sa (subcallosal area) Broca's parolfactory area.
area under the curve (AUC) the area enclosed between the curve of a probability with nonnegative values and the axis of the quality being measured; of the total area under a curve, the proportion that falls between two given points on the curve defines a probability density function.
visual a's three areas (first, second, and third visual areas) of the visual cortex. The first visual area is better known as the striate cortex.
vocal area rima glottidis.
Wernicke's area originally a name for a speech center thought to be confined to the posterior part of the superior temporal gyrus next to the transverse temporal gyri; the term now refers to a wider zone that also includes the supramarginal and angular gyri.

area under the curve

Clinical pharmacology The amount of a therapeutic agent that is present in the circulation in a determined time period, often 24 hrs. See Therapeutic drug monitoring.

area under the curve

,

AUC

The integrated quantity of drug (the serum drug concentration with respect to time after taking a single dose).
References in periodicals archive ?
The z-score table indicates that this would contain 19% on each side or 38% of the area under the curve. The appraiser would report a confidence level of 38% that the value range was between $900,000 and $1,100,000.
So, for noncoherent addition of waves, the area under the curve of temporal motion of intensity of AE does not depend on the speed of the load's application.
Area under the curve (ug.h/ml) of meloxicam in dogs following intravenous administration at dose of 0.2 mg.kg -1 bwt (n-8)
In the realm of proteomics, a three-amino acid profile detectable in saliva that exploits the hypermetabolic and hypercatabolic nature of cancer was found to have an area under the curve of 0.916 for differentiating women with early breast cancer from unaffected peers (Clin Chim Acta.
After running several good shots, the user can go to the new software's Statistics page and examine the minimum, maximum, and average values for two key parameters--the maximum point in the cycle curve (Te) and the Power Factor (Pf), or area under the curve. The user can then set alarm limits for those factors, but knowing where those limits should be set requires empirical data on how much variation in those values will produce a bad shot.
InSea2 also induced a 22% reduction in initial insulin production and an overall 6% reduction in the area under the curve of the insulin response.
* the cumulative amount of heat exposure during the distribution process (the area under the curve), and
The area under the curve from x = 1 to x = a where a >1 is determined by the area of a rectangle of height 1 and length (a - 1), as illustrated in the figure.
A tensilgram in engineering language is a stress-strain diagram and the area under the curve is the thermodynamic equivalent of work (figure 1).
For the regression versus progression outcome, the highest area under the curve was 0.735 with a combination of S5 and cytology; no additional prognostic information was provided by HPV16/18- and HPV16/18/31/33-genotyping.
Natera announced clinical validation study results published in the Journal of Clinical Medicine, demonstrating the highly accurate performance of its donor-derived cell-free DNA test for active allograft rejection in kidney transplant recipients, including higher sensitivity and nearly 18% higher area under the curve than the competitive dd-cfDNA assay.1,2 The study also reports the first accurate detection of T-cell mediated rejection and subclinical rejection.

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