Arctium lappa


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burdock

Chinese medicine
A biennial herb rich in essential oils, arctiol, fukinone, volatile (acetic, butyric, isovaleric) and propionic acids, inulin (up to 50% by weight), non-hydroxyl (lauric, myristic, palmitic, and stearic) acids, polyacetylenes, tannic acid and taraxasterol; the seeds and roots are anti-inflammatory, antimicrobial, antipyretic, antitussive, diaphoretic, diuretic, expectorant and laxative. Burdock is used for abscesses, bronchitis, chickenpox, low back pain, pulmonary congestion, syphilis and urethritis; the seeds are used to treat colds, measles, sore throat and tonsillitis; the roots and leaves are used for rheumatic complaints and gout.

Herbal medicine
Burdock is used by Western herbologists internally for bacterial and fungal infections, cystitis, fever, recuperation from strokes, renal disease, as a gastrointestinal tonic, to detoxify various organs; it is used topically for skin conditions such as acne, bites, dandruff, eczema, psoriasis, gout and leprosy.

Toxicity
Burdock should not be used in pregnancy, as it stimulates uterine contraction, or in young children.

Arctium lappa,

n See burdock.

Arctium lappa

a temperate zone plant with burrs which causes granular stomatitis in the dog. Called also burdock.
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References in periodicals archive ?
In this study a fraction containing the lactone sesquiterpene onopordopicrin (ONP) from Arctium lappa was administered orally as either 25mg/kg daily or 50mg/kg daily 48, 24 and 1 hour before the induction of colitis in rats by the administration of 2,4,6 trinitrobenzene sulfonic acid (TNBS).
These results, while preliminary and only reflecting a small animal study, suggest a potential therapeutic use for Arctium lappa in inflammatory bowel disease such as Crohn's disease and ulcerative colitis.
Burdock used as an anti-inflammatory
Seeds of Arctium lappa were collected from the Neuenheimer Feld, Heidelberg, Germany in July 2011.
Extraction and isolation of lignans from Arctium lappa
lappa extract were performed as described in our article: natural lignans from Arctium lappa as novel antiaging agents in Caenorhabditis elegans (submitted to Phytochemistry).
In the present study, we found that the major lignans isolated from Arctium lappa seeds possess promising MDR reversal activities in CEM/ADR 5000 and CaCo2 cell lines, which overexpress P-gp and other ABC transporters.
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells
Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa U.
Mechanism of arctigenin-mediated specific cytotoxicity against human lung adenocarcinoma cell lines
Fructus Arctii, the dried fruits of Arctium lappa L.
Arctiin was isolated and purified from the fruits of Arctium lappa L.
In summary, arctiin, isolated from the fruits of Arctium lappa, has ameliorative effects on cBSA-induced glomerulonephritis in rats.
Effects of extract from Arctium Lappa on the immunology and blood glucose in rats.
Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats

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