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amyloid precursor protein
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
APPA gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
APPAmyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.