apolipoprotein D

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Related to apolipoprotein D: apolipoprotein C, Apolipoprotein E, PubMed

ap·o·lip·o·pro·tein D

an apolipoprotein found in HDL. It forms a complex with LCAT and appears to be involved in the transport of bilin.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 3q26.2-qter that encodes apolipoprotein D, a protein which is part of high-density lipoprotein (HDL) and forms a macromolecular complex with lecithin-cholesterol acyltransferase (LCTA). It is thought to play a role in the transport and binding of bilin, and may transport different ligands in different contexts. ApoD has a high degree of homology to retinol-binding protein and other members of the alpha-2 microglobulin protein superfamily of carrier proteins, or lipocalins.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Apolipoprotein D. Biochim Biophys Acta 2000;1482:185-98.
Apolipoprotein D expression absence in degenerating neurons of human central nervous system.
Astrocytes synthesize and secrete the lipophilic ligand carrier apolipoprotein D. Neuroreport 1995;6:653-7.
Expression pattern of lipocalin apolipoprotein D during mouse embryogenesis.
Modulation of apolipoprotein D and apolipoprotein E expression in rat hippocampus after entorhinal cortex lesion.
Apolipoprotein D in the Niemann-Pick type C disease mouse brain: An ultrastructural immunocytochemical analysis.