apolipoprotein B(redirected from ApoB 100)
an apolipoprotein found in chylomicrons, LDL, VLDL, and IDL. Elevated in the plasma of patients with familial hyperlipoproteinemia; it exists in two forms, B-100 and B-48.
APOBA gene on chromosome 2p24-p23 that encodes apolipoprotein B, the main apoliprotein of chylomicrons and low-density lipoproteins, which appears in plasma as two main isoforms: apoB48 (which is synthesised exclusively in the gut) and apoB100 (which is synthesised in the liver).
APOB mutations cause hypobetalipoproteinaemia, normotriglyceridemic hypobetalipoproteinaemia, and hypercholesterolaemia due to ligand-defective apoB.