APOA2

(redirected from Apo-AII)

APOA2

A gene on chromosome 1q21-q23 that encodes apolipoprotein A2, a protein component of high-density lipoprotein (HDL), which is present in plasma as a monomer, homodimer or heterodimer with apolipoprotein D.

Molecular pathology
APOA2 mutations cause apolipoprotein A2 deficiency or hypercholesterolaemia.
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Their major proteins are apo-AI, apo-AII, and smaller amounts of C apolipoproteins and apo-E.