disease-modifying antirheumatic drug

(redirected from Antirheumatic agents)

disease-modifying antirheumatic drug (DMARD)

a classification of antirheumatic agents referring to their ability to modify the course of disease, as opposed to simply treating symptoms such as inflammation and pain. Agents in this group include auranofin, azathioprine, cycloSPORINE, gold salts, hydroxychloroquine, leflunomide, methotrexate, D-penicillamine, and sulfasalazine.

disease-modifying antirheumatic drug

DMARD Rheumatology Any agent–eg, azathioprine, gold, cyclophosphamide, hydroxychloroquin, and MTX–which slows the rate of joint destruction in rheumatoid arthritis

disease-modifying antirheumatic drug

Abbreviation: DMARD
A drug that is used to treat rheumatoid arthritis and acts more slowly but more effectively than nonsteroidal anti-inflammatory drugs. Such drugs include hydroxychloroquine, methotrexate, and tumor necrosis factor inhibitors.
Synonym: slow-acting antirheumatic drug
See also: drug
References in periodicals archive ?
Among those are antirheumatic agents such as anti-TNF biologics (3) and methotrexate.
Hydroxychloroquine, which may have antispirochetal and anti-inflammatory effects, may be used in the negative PCR patients, and "there may be a role for certain disease-modifying antirheumatic agents in the management of chronic Lyme arthritis, but experience with their use in this setting is limited," they said.
It's unclear whether disease-modifying antirheumatic agents (DMARDs) as first-line therapy in nonrheumatoid rheumatologic diseases are effective because the question has not been studied.
6) Despite the proliferation of antirheumatic agents, methotrexate, a structural analogue of folic acid, remains the gold standard among DMARDs.
Conventional, small molecule, disease-modifying antirheumatic agents (DMARDs) remain the mainstay of early-line treatment, but patients who fail such agents, patients with severe disease, or patients in whom conventional DMARDs are contraindicated are treated with biological DMARDs.
Purpose of this contract is to obtain anti-inflammatory and antirheumatic agents (M01) and opioids (N02A) of salicylic acid and its derivatives (N02BA) and aniline (N02BE).
A diagnosis of rheumatic disease and use of antirheumatic agents are purported to be risk factors for tuberculosis as well.
Despite the large number of tuberculosis cases in this stud); the prevalence of antirheumatic agent use was low," and thus independent effects for patients on antirheumatics could not be assessed reliably, the researchers noted.
Cytotoxic and antirheumatic agents may treat vascular, ocular, neurological, and joint manifestations.
Over the forecast period, the GI market's growth will be determined by the growth of the immunosuppressants and antirheumatic agents.
Methotrexate has shown inconsistent efficacy, while other antirheumatic agents, such as sulfasalazine and gold have shown few, if any, benefits.
Discover which autoimmune drug classes will provide the greatest franchise growth potential and identify the growth drivers of major treatment classes including immunosuppressants, antirheumatic agents, COX-II inhibitors, NSAIDs and corticosteroids.