Tinidazole, an antiprotozoal agent
that has been used in other countries for more than 25 years, also received Food and Drug Administration approval for treating giardiasis, intestinal amebiasis, and amebic liver abscess.
All three metabolites possessed toxicity on mammalian cells, which might limit their use as antiprotozoal agents
Summary: Betulinic acid (triterpene) has shown an immense potential towards the development of anticancer, antiviral, antimalarial, antifungal, antioxidant and antiprotozoal agents
. Cis-platin (cytotoxic agent) has diverted attention of chemists towards organotin complexes with marked pharmacological activities.
This industry includes establishments that produce antibiotics to treat bacterial infections, anti-viral drugs to treat viral infections, anti-fungal drugs to treat fungal infections, anti- helminthic drugs to kill internal parasites and antiprotozoal agents
Glycosides are also considered promising antiprotozoal agents
, particularly against Leishmania spp.
Among the topics are animal fecal actinomycetes as a new source for the discovery of drug leads, novel antimicrobial and anticancer drugs from bacteria, antimicrobial and natural compounds from edible mushrooms, antimicrobial compounds from rhizosphere bacteria and their role in plant disease management, and fighting microbe with microbe using antiprotozoal agents
derived from natural soil and aquatic actinobacteria.
Thus, most antiprotozoal agents
seem to perform poorly after nitroimidazole has failed.