anti-mullerian hormone

(redirected from Antimullerian hormone)

mül·le·ri·an in·hib·it·ing sub·stance (MIS),

a 535-amino acid glycoprotein secreted by the Sertoli cells of the testis. It is related to inhibin.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 19p13.3 that encodes anti-Müllerian hormone, a member of the transforming growth factor-beta gene family, which mediates male sexual differentiation. AMH causes regression of Müllerian ducts, which would otherwise differentiate into the uterus and fallopian tubes.
Molecular pathology
AMH mutations result in persistent Müllerian duct syndrome.

müllerian inhibiting substance

A 59 kD glycosylated preproprotein of the TGF-beta family encoded by AMH on chromosome 19p13.3 and produced by Sertoli cells in the prepubertal testes, which promotes müllerian duct involution during normal male sexual differentiation. The lack of MIS results in persistent müllerian duct syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: A longitudinal study.
4 AMH: Antimullerian hormone; BMI: Body mass index; AFC: Antral follicle count.
Effect of detorsion alone and in combination with enoxaparin therapy on ovarian reserve and serum antimullerian hormone levels in a rat ovarian torsion model.
In addition to estrogen, testosterone, progesterone, and their associated metabolites, other reproductive and pituitary endocrine markers have sex-specific ranges, including the following: FSH, LH, sex hormone binding globulin, antimullerian hormone, and prolactin.
(12) The evaluation includes blood tests for follicle-stimulating hormone (FSH), estradiol, and antimullerian hormone (AMH) as well as ultrasound imaging of the ovaries.
von Bergh et al., "AntiMullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment," Molecular Human Reproduction, vol.
Lack of the vitamin can also contribute towards a decreased reserve of eggs in women, by influencing AMH (Antimullerian Hormone) levels, which can affect egg quality and pregnancy rates.
Discordances between follicle stimulating hormone (FSH) and antimullerian hormone (AMH) in female infertility.