antihypertensive

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Related to Antihypertensive agents: antihypertensive drugs, anencephaly, hypoxia

antihypertensive

 [an″te-, an″ti-hi″per-ten´siv]
effective against hypertension.
antihypertensive agent an agent that reduces high blood pressure; there are many different types of drugs that do this. diuretics inhibit the reabsorption of sodium in the renal tubules, causing an increase in urinary excretion of sodium and a decrease in the plasma volume and extracellular fluid volume. Drugs that act on adrenergic control of blood pressure include beta-adrenergic blocking agents such as propranolol, which act at beta-adrenergic receptors in the heart and kidneys to reduce cardiac output and renin secretion, and others such as methyldopa that act on alpha-adrenergic mechanisms in the central or sympathetic nervous system to reduce peripheral vascular resistance. vasodilators act directly on the arterioles to produce the same effect. Almost every case of hypertension can be controlled by one of these drugs or a combination of them. The proper combination is determined by the response of the individual patient. In some cases several drugs must be tried before the right combination is found.
Patient Education. Instruction of the patient and significant others is an essential part of antihypertensive therapy. Learning objectives are based on the patient's particular regimen of drug therapy, allowance of sodium intake, and other dietary restrictions, such as a low-calorie diet to combat obesity.

Some antihypertensive drugs can produce acute hypotensive reactions. The patient will need to know how to prevent a hypotensive reaction and what measures to take should such a reaction occur.

Prevention of a hypotensive reaction includes avoiding hot baths and sudden immobility after exercise, both of which promote vasodilation and a lowering of arterial pressure. The patient also should be aware of the effect of sudden changes in position that can precipitate an attack of orthostatic hypotension. Pooling of blood in the lower limbs can divert it from the brain and other vital organs. This can sometimes be avoided by moving about frequently instead of standing motionless for long periods of time. Elastic stockings also help promote venous return from the legs and help prevent fainting from decreased cerebral blood supply.

Acute hypotension can be serious, but milder hypotensive reactions with faintness and weakness can be relieved at home if the patient lies down and elevates his lower extremities above the level of his head and flexes the thigh muscles to encourage the flow of blood from his feet and legs to his brain.

The patient on a diuretic that is not potassium-sparing will need instruction on the symptoms of potassium deficit, how to avoid potassium depletion, and when to notify the doctor should hypokalemia occur.

Limitation of sodium intake can be very confusing and emotionally stressful to the uninstructed patient. In order to comply with the prescribed restriction of sodium the patient will need to know about satisfying substitutes and alternative seasonings for food, to be aware of the necessity of reading labels carefully when buying prepared food and over-the-counter medications, and to recognize the relationship between sodium and high blood pressure and the reasons why high sodium intake is harmful to health and well-being.

an·ti·hy·per·ten·sive

(an'tē-hī-per-ten'siv),
Indicating a drug or mode of treatment that reduces the blood pressure of hypertensive patients.

antihypertensive

(ăn′tē-hī′pər-tĕn′sĭv, ăn′tī-)
adj.
Reducing or controlling high blood pressure.
n.
An antihypertensive drug.

antihypertensive

adjective Referring to an agent or mechanism that counters hypertension.

noun An agent used to manage hypertension.

antihypertensive

adjective Referring to an agent or mechanism that reduces HTN noun An agent used to manage HTN

an·ti·hy·per·ten·sive

(an'tē-hī-pĕr-ten'siv)
Indicating a drug or mode of treatment that reduces the blood pressure of people with hypertension.

antihypertensive

1. Acting against high blood pressure (HYPERTENSION).
2. A drug used in the treatment of high blood pressure.

Antihypertensive

Used to describe drugs or treatments designed to control hypertension, or high blood pressure.
Mentioned in: Hyperaldosteronism

an·ti·hy·per·ten·sive

(an'tē-hī-pĕr-ten'siv)
Indicating a drug or treatment that reduces the blood pressure of hypertensive patients.
References in periodicals archive ?
[1] However, there is controversy with regard to treatment of mild-to-moderate elevations in BP because of exposure of the fetus to antihypertensive agents, even if it is over a relatively short period and without any evidence of benefit to the mother.
Additionally, we did not include subjects diagnosed with hypertension for the first time, since it is not feasible to evaluate the possible influence of antihypertensive agents in these patients.
The antihypertensive agent dose remained unaltered.
Two (18.2%) patients diagnosed with mild to moderate pre-eclampsia on two different types of antihypertensive agents were being treated as outpatients (Table 2) with poor blood pressure control.
IV labetalol, IV dihydralazine and oral nifedipine are the commonly used antihypertensive agents. The contraindications to and compelling indications for the available rapid-acting agents must be considered when choosing a particular drug.
In consideration of the restricted time window available for alteplase treatment as well as the potential for improved patient outcomes with earlier alteplase administration, it would be valuable to determine if the required blood pressure targets could be attained more rapidly with the use of specific antihypertensive agents. This study aimed to compare the antihypertensive effects of labetalol, nicardipine, and hydralazine in this patient population.
According to multivariable Logistic regression analysis, preoperative use of two or more antihypertensive agents (odds ratio, 2.75; 95% confidence interval [ CI ], 1.25-6.09; P = 0.012) and high LDL level (odds ratio, 2.21; 95% CI , 1.01-4.83; P = 0.048) were independently associated with the persistence of hypertension.
The doctors have misconception about the cost effectiveness of certain antihypertensive agents. The outcomes of this study should be reflected for designing plans for patient awareness and education of health providers; and also considered for periodically updating therapeutic guidelines for blood pressure control.
Resistant hypertension is defined as "Suboptimal control of blood pressure despite using three antihypertensive agents inclusive of a diuretic, and patients who need 4 or more drugs to control blood pressure.
Doses of antihypertensive agents, including angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, and diuretics, were adjusted during the study period to maintain the target BP level of <130/80 mmHg.
Several classes of antihypertensive agents have been evaluated for efficacy and safety in the management of hypertension in patients receiving hemodialysis.
"This is the first study to consider sex as an element in the selection of antihypertensive agents or base the choice of a specific drug on the various factors accounting for the elevation in blood pressure," lead author of the study, Carlos Ferrario, said.