Esteban said in his study that both disc diffusion and dilution method was able to measured sensitivity rate of antifungal drug
with no significant difference.6 Cordoba et al.14 in their study about comparison of disc diffusion and dilution method, said that disc diffusion method could not estimate MIC value of the drug, but it can determined the sensitivity of Malassezia spp.14
Taking into account, the proven/probable IFI incidence rate estimated in this study, 4.8 per 1000 discharges (95% CI 0.7-8.9), we estimate that in one year the total number of proven/probable IFIs treated with an antifungal drug
to be approximately 30,091 patients (95% CI 4396-55,785) (Table 6).
sacchari was evaluated against 11 antifungal drugs
(including amphotericin b, itraconazole and voriconazole) (13).
The susceptibility testing of fungi to antimycotic drugs, including that of yeasts, was until recently performed only rarely because of factors such as: The cases necessitating systemic antifungal treatment were relatively rare; the number of antifungal drugs
was limited; the incidence of resistance to the drugs was rare; and most importantly, correlation between in vitro and in vivo results was questionable.
Plasma concentrations of antifungal drug
in Japanese quail after administration via impregnated subcutaneous implant.
The ongoing change in the epidemiology of Candida species is in parallel with the emergence of antifungal drug
resistant Candida species (14).
Eleven of the 91 strains tested (12.1%) were classified as resistant to at least two antifungal drugs
. Table 2 summarizes the resistance profile of the Brazilian tested clinical strains of C.
A better approach is to fabricate such acrylic dentures which may act as DRDs (Drug releasing devices) from which antifungal drugs
elute and inhibit microbial growth.4 Most commonly used agents for such purposes are chlorhexidine acetate and digluconate which are commonly used as antiseptic mouthwash due to its broad-spectrum antimicrobial activity.5 However, when used as a mouth wash, most of the agents are removed from the mouth during the first hour, due to the diluting effect of the saliva.
Chronic paronychia may be treated with an over-the-counter cream containing an antifungal drug
but if there's a secondary infection your doctor may prescribe stronger antifungals and oral antibiotics.
resistance: mechanisms, epidemiology, and consequences for treatment.
In the past, antifungal drug
resistance was not known to exist, but today primary and secondary antifungal drug
resistance has been proved by extensive multicentre studies.
In comparison, the conventional antifungal drug
, Fluconazole, was only able to inhibit additional fungal growth, and the infection exhibited drug resistance after six treatments.