Anticoagulants


Also found in: Dictionary, Thesaurus, Encyclopedia.

Anticoagulants

Drugs that suppress, delay, or prevent blood clots. Anticoagulants are used to treat embolisms.

anticoagulants

agents (warfarin, aspirin, clopidogrel, coumarin, heparin) that prevent or reduce blood coagulation; prescribed to prolong clotting time or prevent intravascular clot formation, e.g. in patients with a history of stroke, ischaemic heart disease, peripheral vascular disease, atrial fibrillation or deep-vein thrombosis; side-effects include prolonged bleeding, easy and excessive bruising; concomitant non-steroidal anti-inflammatory drugs, carbamazepine, antifungal medications, erythromycin, clarithromycin, metronidazole and broad-spectrum oral antibiotics (e.g. amoxicillin) increase anticoagulant effects
References in periodicals archive ?
In the event of a blood clot requiring treatment, she says that NOACs work more quickly than warfarin and don't require overlapping of medications, whereas warfarin needs to overlap with a shortacting anticoagulant, such as lowmolecular-weight heparin, for about five days until warfarin takes effect.
With the recommendation of usage of novel oral anticoagulants (NOAC) by International guidelines in line with their established safety, efficacy and compliance, we expect decrease of warfarin use at a CAGR of negative 3.
Wahl7,14 in a review found there was little or no difference in terms of blood loss after dental surgery between patients who were receiving anticoagulants and those whose coagulation was normal.
Gersh was also critical of another common practice in stroke prevention in atrial fibrillation: concomitant use of aspirin with an oral anticoagulant.
Baird cautions that news reports of safety issues with some nursing home residents taking anticoagulants aren't representative of all facilities.
6 percent of patients younger than 65 with AF would now qualify for anticoagulants.
CHICAGO -- Patients with atrial fibrillation who start treatment with a new oral anticoagulant may spend more on their medication than if they were prescribed generic warfarin, but their overall health care costs could be the same, based on an analysis of health care expense records for more than 4,500 U.
Bayer HealthCare announced today that new data from clinical trials and real-world studies to be presented at the American Heart Association (AHA) Scientific Sessions 2014 in Chicago, Il, USA, November 15-19, 2014, will provide important insights regarding the clinical utility of its novel oral anticoagulant Xarelto (rivaroxaban) for stroke prevention in patients with atrial fibrillation (AF).
Another worrying finding was that oral anticoagulants were underprescribed in elderly patients, with aspirin alone more commonly prescribed.
We systematically searched MEDLINE (1946 to January 2013) using both Ovid SP and PubMed search interfaces, EMBASE (1974 to Week 1, 2013), BIOSIS Previews (January 2013), Web of Science with Conference Proceedings (January 2013), and the Cochrane Central Register of Controlled Trials (January 2013) databases; we looked for studies assessing the effect of anticoagulants and antiplatelet agents on the efficacy of BCG intravesical therapy in patients with bladder cancer.
After written informed consent, a blood sample was obtained from 25 healthy voluntary blood donors with no personal or family history of bleeding or thrombotic disorders and no recent use of nonsteroidal anti-inflammatory drugs or any type of anticoagulants.

Full browser ?