reporter gene

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reporter gene

, reporter
A gene whose products are easily detected or measured. In biochemical research it is linked to a gene of interest and used to signal to researchers that the gene has been successfully inserted into a cell or chromosome.

reporter gene

a test GENE with a coding region whose PHENOTYPE can be easily detected. Ideally it should be possible to assay the phenotype quantitatively. The reporter gene may be fused immediately DOWNSTREAM of a regulatory region so that its expression (see GENE EXPRESSION is under the influence of that region. The extent and pattern of expression of the reporter gene construct, determined by assay of phenotype, can be used to analyse gene regulation.
References in periodicals archive ?
This agreement enables Sanofi-Pasteur to implement the StabyExpress technology in its production of recombinant vaccines and therefore to be able to produce them efficiently without using antibiotic markers.
The inclusion of these antibiotic markers have been strongly opposed especially because it is possible for this genetic material to move to bacteria in the soil or from the genetically engineered food into gut bacteria, increasing the possibility of antibiotic resistance.
Although there is limited knowledge about the risk of compromising the therapeutic value of antibiotics, antibiotic markers may be banned in agricultural crops in the future (Kuiper et al., 2001; Miki and McHugh, 2004).

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