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We investigated the effect of antiandrogens on the hAR by performing competitive assays.
He has found that antiandrogens are most helpful when administered near the of Fender's release date.
Recent interest in reproductive effects of antiandrogens has focused on the phthalates, particularly diethylhexyl phthalate (DEHP) and dibutyl phthalate (DBP), whose antiandrogenic effects have been directly demonstrated in rodent models (Gray et al.
As is the case in the major markets, LHRH agonists and antiandrogens are by far the most frequently prescribed therapies for treatment across all stages of prostate cancer in Russia, with locally manufactured Buserelin as the most popular LHRH-agonist," said Decision Resources Analyst Natalia Reoutova, M.
9 Abbreviations: AA, antiandrogenic, refers to known antiandrogens (not assessed by QSAR); [EC.
Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens.
To study the antiandrogenic activity, the cells were first exposed to the putative antiandrogen ([10.
As yet, these regulatory efforts have taken little account of realistic human exposures to several phthalates and other antiandrogens simultaneously (Blount et al.
Consistent with this notion, combinations of antiandrogens at NOAEL doses have been induced significant synetgistic effects in vivo (Hass et al.
Moreover, all of the patients had previously failed treatment with LHRH analogs and antiandrogens, while 22 patients (50%) had failed treatment with diethylstilboestrol and 20 patients (45%) had failed treatment with steroids.
In the treatment of sexual deviations in men, administration of Salvacyl(R)/Moapar(R) every 3 months is an advantage over daily oral forms or intra-muscular weekly injections required with antiandrogens such as cyproterone acetate (CPA) and medroxyprogesterone acetate (MPA) and there are fewer side effects.