antineutrophil cytoplasmic antibodies

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antineutrophil cytoplasmic antibodies (ANCA),

autoantibodies found in some autoimmune diseases, recognized by their reactivity with cytoplasmic antigens in neutrophils; two groups are recognized: c-ANCA, reacting with proteinase 3, is found in polyangiitis and Churg-Strauss syndrome; p-ANCA, reacting with myeloperoxidase is found in Wegener granulomatosis.
References in periodicals archive ?
Anti-neutrophil cytoplasmic antibody (ANCA) was negative by the indirect immunofluorescence method.
Blood tests were positive for anti-neutrophil cytoplasmic antibody (c-ANCA) and anti-proteinase 3 (PR3) antibodies.
The rest of the laboratory data was essentially unremarkable, including serum complement levels, anti-neutrophil cytoplasmic antibody, anti double-stranded DNA, human immunodeficiency virus, hepatitis serology, anti-phospholipid antibodies, anti-glomerular basement membrane antibody, and anti-neutrophilic cytoplasmic antibodies.
C also is positive for perinuclear-staining anti-neutrophil cytoplasmic antibody (pANCA) but negative for cytoplasmic-staining ANCA (cANCA) with normal C3 and C4 levels.
A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn's disease.
To exclude vasculitis perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA), cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) and anti neutrophil antibodies titres can be obtained.
The results of other serologic testing of antinuclear antibody spectrum, anti-neutrophil cytoplasmic antibody, rheumatoid factor, anticardiolipin antibody, angiotensin converting enzyme, syphilitic serologic test, and paraneoplastic tests were all negative.
Tests for anti-neutrophil cytoplasmic antibody (ANCA) and anti-cardiolipin antibodies (IgM and IgG) with anti-DNA antibodies were negative.
Her Rheumatoid Factor (RF), cytoplasmic Anti-neutrophil Cytoplasmic Antibody (c ANCA) and perinuclear ANCA were negative but antinuclear antibody (ANA) and anti double stranded DNA (anti ds DNA) analysis were positive.
False positive' perinuclear and cytoplasmic anti-neutrophil cytoplasmic antibody results leading to misdiagnosis of Wegener's granulomatosis and/or microscopic polyarteritis.
A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in ulcerative colitis but not in Crohn's disease.