antifreeze

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antifreeze

A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck and other cooling systems for internal combustion engines to substantially reduce the freezing point of the coolant.

Antifreeze has long had currency as a surrogate inebriant despite it being associated with acidosis and renal shutdown (due to ethylene glycol), as well as blindness (due to methanol).

Clinical findings
In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with nausea, vomiting, seizures, coma or death (at levels above 100 ml of ethylene glycol).

antifreeze

Toxicology A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck, and other cooling systems for internal combustion engines to substantially ↓ the freezing point of the coolant; antifreeze has long had currency as a surrogate inebriant, despite its being associated with acidosis and renal shutdown–ethylene glycol and blindness–methanol Clinical In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with N&V, seizures, coma, death, at levels above 100 ml of ethylene glycol. See Leukovorin rescue. Methotrexatre
References in periodicals archive ?
They said after a cat ingests anti-freeze, an antidote has to be administered within three to four hours, so it was too late."
They found Harry had anti-freeze on his neck and, as a result of cleaning, in his stomach.
" It could be that someone has been draining anti-freeze from their car and somehow the cats have come into contact with it, or that someone has left their garage open with a jug of anti-freeze lying around and the cats have drunk from it.
Poisoned Pet cat Louis passed away after ingesting anti-freeze
The machine has a capacity of making up-to 37000 bottles of 1 liter of Anti-Freeze Coolants or Brake Fluid per day.
"Prestone" anti-freeze helps keep our ships in fighting trim!
PC Dave Allen from North Wales Police said: "Early indications point towards the animals having been poisoned, possibly with anti-freeze, but at this stage we are keeping an open mind on it being a deliberate act or accidental."
"We've had incidents with anti-freeze before where it's been a mistake, but we're in May and there's no reason for anyone to be using it.
DIANNE CUNNINGHAM IS WARNING CAT OWNERS TO KEEP THEIR PETS SAFE AFTER HER CAT WAS KILLED BY SUSPECTED ANTI-FREEZE POISONING Danielle Wilson: "I lost my cat to anti-freeze poisoning.