The company is also developing its anti-arrhythmic drug
candidate, budiodarone, for the potential treatment of refractory atrial fibrillation, defined as those patients who have failed at least one first line therapy with anti-arrhythmic drugs
or catheter ablation as well as ventricular tachycardia in patients with implantable cardioverter defibrillators.
Patient's weight was measured to allow dose calculations of anti-arrhythmic drugs
per kilogram of weight.
RVOT: right ventricular outflow tract; ASC: aortic sinus cusp; PVC: premature ventricular contractions; LV: left ventricular; SR: sinus rhythm; VT: ventricular tachycardia; AAD: anti-arrhythmic drugs
. Fisher's exact test was used to compare percentages and t-test to compare means.
 Close monitoring and dose adjustment are required in elderly patients and those with renal impairment, and when used with other anti-arrhythmic drugs
. Indeed, in an article in the Forum section in this edition of SAMJ, Opie  states that there are few arguments in favour of the use of digoxin to control rate in atrial fibrillation.
to slow a rapid heartbeat and beta-blockers.
Some of these are associated with severe clinical signs warranting their immediate management with anti-arrhythmic drugs
. The present investigation was therefore undertaken to study the prevalence of arrhythmias in dogs along with their management approach.
"Given the risk of complications with ablation, our data support the current guidelines recommending anti-arrhythmic drugs
as first-line treatment in most patients with paroxysmal atrial fibrillation," wrote Dr.
A diagnosis of AF is usually followed by treatment with anti-arrhythmic drugs
designed to normalize your heart rate.
MEDICATIONS Options include anti-arrhythmic drugs
, beta blockers and calcium channel blockers.
At an average follow-up of one year (12.0 +/= 1.8 months post remapping), 71% of patients remained free from AF and off anti-arrhythmic drugs
In the U.S., anti-arrhythmic drugs
effectively stop episodes of afib in about 30 percent of patients.