antifreeze

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Related to Anti freeze: ethylene glycol

antifreeze

A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck and other cooling systems for internal combustion engines to substantially reduce the freezing point of the coolant.

Antifreeze has long had currency as a surrogate inebriant despite it being associated with acidosis and renal shutdown (due to ethylene glycol), as well as blindness (due to methanol).

Clinical findings
In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with nausea, vomiting, seizures, coma or death (at levels above 100 ml of ethylene glycol).

antifreeze

Toxicology A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck, and other cooling systems for internal combustion engines to substantially ↓ the freezing point of the coolant; antifreeze has long had currency as a surrogate inebriant, despite its being associated with acidosis and renal shutdown–ethylene glycol and blindness–methanol Clinical In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with N&V, seizures, coma, death, at levels above 100 ml of ethylene glycol. See Leukovorin rescue. Methotrexatre
References in periodicals archive ?
The RSPCA investigates a number of cases where cats are believed to have ingested anti freeze, due to either accidental or deliberate incidents.
From the shock waves that followed the revelation that a handful of producers were sweetening wines with a chemical found in anti freeze, the industry has fought back and now boasts a selection of world-class wines, especially dry whites.
Dianne Cunningham's cat Tyrion, who died after being poisoned with anti freeze