anthracycline(redirected from Anthracyclines)
a class of antibiotics isolated from cultures of Streptomyces peucetius; it includes the antineoplastic agentsdaunorubicin and doxorubicin. The use of these drugs is limited by a chronic, cumulative, dose-related toxicity resulting in irreversible congestive heart failure.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Anticancer agent consisting of three moieties: a pigmented aglycone, an amino sugar, and a lateral chain. Examples include doxorubicin, daunorubicin, and daunomycin (pirubicin).
Farlex Partner Medical Dictionary © Farlex 2012
anthracyclineOncology A chemotherapeutic used in leukemia to prevent cell division Adverse effects Dose-dependent stomatitis, N&V and BM suppression which 'maxes' at ± 10 days; alopecia is normal; extravasation at IV injection site causes severe, protracted ulcers and necrosis. See Chemotherapy, Daunorubicin, Doxorubicin, Idarubicin.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.