Antabuse


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Antabuse

 [an´tah-būs]
trademark for a preparation of disulfiram, used in the treatment of alcoholism; it causes nausea and other distressing symptoms in persons who ingest alcohol while taking it.

Antabuse

(ăn′tə-byo͞os′)
A trademark for the drug disulfiram.

Antabuse®

Disulfuram, see there.

Antabuse

Disulfiram. A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.
References in periodicals archive ?
The formation of acetaldehyde in the organism after ingestion of Antabuse (tetraethylthiuram-disulphide) and alcohol.
(ii) She also attends Dr C, where the giving of periodic blood tests and the taking of Antabuse [a drug prescribed to recovering alcoholics to help them abstain from drinking alcohol] are vital ingredients to prevent her returning to alcohol.
L'ambiguite des medicaments--oscillant entre controle social oppressif et maitrise de soi-meme--se manifeste notamment dans le principal remede qui traite l'alcoolisme au Danemark, l'Antabuse (ce medicament interfere avec la decomposition de l'alcool dans le corps et cause des effets secondaires desagreables).
Some treatment programs have tried this on an informal basis; (97) but even a physical committing device like disulfiram (Antabuse), which makes alcohol sickening for a period of days, has been shown not to increase sobriety after one year in the absence of a highly structured social program.
dizziness, antabuse reactions (alcohol content), hyperlipidemia, hyperglycemia, lipodystrophy, hepatitis indinavir (IDV) Kidney stones, GI Take 2 capsules/dose (Crixivan[R]) (nausea, diarrhea, q 8h on an empty vomiting, abdominal stomach (1 hr before pain); neurologic: or 2 hours after a headaches, insomnia, meal) or with a light change in taste, dry meal (skim milk, skin, hair loss, juice, coffee, tea, hyperlipidemia, dry toast, corn hyperglycemia, flakes).
He had Antabuse tablets inserted into his stomach to keep him on the wagon after being warned that just one more drink could kill him.
He cut out alcohol and had Antabuse tablets inserted into his stomach to keep him on the wagon after he was warned just one more drink could kill him.
Over the years she tried a number of tricks to limit Bishop's drinking, such as hiring a housekeeper to keep an eye on things and empty hidden bottles of alcohol, and getting a prescription for Antabuse, which she sometimes persuaded Bishop to ingest.
Disulfiram (Antabuse) decreases drink frequency, but is no better than placebo for other outcomes.
They said a new treatment was needed because other medications, such as Antabuse, sometimes cause nausea and headaches.
A number of drugs, notably disulfiram (marketed as Antabuse) and naltrexone (trademarked as ReVia), can help some alcoholics avoid relapsing.