Antabuse


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Antabuse

 [an´tah-būs]
trademark for a preparation of disulfiram, used in the treatment of alcoholism; it causes nausea and other distressing symptoms in persons who ingest alcohol while taking it.

Antabuse

(ăn′tə-byo͞os′)
A trademark for the drug disulfiram.

Antabuse

a trademark for an alcohol-use deterrent (disulfiram).

Antabuse®

Disulfuram, see there.

Antabuse

Disulfiram. A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.
References in periodicals archive ?
You have to be cautious with new drugs because when Antabuse first came out, we thought it was a panacea," said Harris.
The pellets, called Antabuse, make a person physically sick if they touch a drop.
Some have described it as ``the Antabuse of weight loss,'' referring to the drug for alcoholism that makes people ill when they drink.
The patient should be informed that alcohol or alcohol-containing preparations should not be taken the day of taking Metronidazole or for 3 days following it due to causing an antabuse effect that includes nausea, vomiting, and cramping.
The consultant said she noticed prescriptions for AZT for AIDS patients, Antabuse for alcoholics, and numerous antidepressant and psychotropic drugs.
At Lota's insistence, in early 1953 Bishop entered a hospital to dry out and there began aversion therapy for the first time, in the form of Antabuse.
All of them had been treated with Antabuse at the psychiatric-neurological department of the university directed by Hans Hoff.
Subsequently, the alcoholic refrains from drinking when antabuse is ingested.
X, in excellent health and without physical complaints, requested a prescription for Antabuse, a medication causing alcohol aversion.
It included daily doses of the antialcohol drug Antabuse and monthly injections of Vivitrol which prevents drug users from relapsing.
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