Also found in: Dictionary, Thesaurus, Encyclopedia.
trademark for a preparation of disulfiram, used in the treatment of alcoholism; it causes nausea and other distressing symptoms in persons who ingest alcohol while taking it.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A trademark for the drug disulfiram.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Antabuse®Disulfuram, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
AntabuseDisulfiram. A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005