annotation(redirected from Annotations)
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annotationBioinformatics A term of art referring to analysis and commentary added to sequence data in databases, which provide contextual information about coding and non-coding sequence within genes, patterning and motifs, similarities, known or predicted protein structure and function, and links to external data (e.g., clinical observations).
Informatics A critical or explanatory note, usually included in a bibliographical entry or reference, to provide additional data.
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annotationprocess used in GENOMICS for analysis of NUCLEOTIDE SEQUENCES to identify the GENES (both PROTEIN-coding and protein non-coding, such as those for rRNA and tRNA), their regulatory sequences (see OPERON MODEL and their functions. Annotation also includes characterization of MOBILE GENETIC ELEMENTS and REPETITIVE DNA. See also BIOINFORMATICS.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005