ankyrin

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an·ky·rin

(ang'ki-rin),
An erythrocyte membranal protein that binds spectrin. A deficiency in ankyrin may lead to a type of hereditary spherocytosis.
See also: nexins.
Synonym(s): anchorin, syndein
[G. ankyra, anchor, + -in]

ankyrin

Any of a family of proteins which mediate the binding of integral membrane proteins to the cytoskeleton, e.g., spectrin to the erythrocyte’s anion exchange (band-III) protein.

ankyrin

(ang′kĭ-rin)
A structural protein in red blood cells that binds cell membrane transport molecules to spectrin.
References in periodicals archive ?
Sorrentino, "Muscle-specific ankyrins and the organization of the sarcoplasmic reticulum in striated muscle cells," Biophysical Journal 86(1): 222a, vol.
Apart from the Ankyrin protein family, another group of proteins, the EPH subfamily, have also been identified to contribute to epilepsy.
Mohler, "Ankyrin protein networks in membrane formation and stabilization," Journal of Cellular and Molecular Medicine, vol.
They found that the specific human gene mutation disrupts the ability of the protein ankyrin to regulate a key protein complex known as the KATP channel.
According to the researchers, a key finding in this study was identifying the ankyrin protein in the pancreatic beta cell, which is a type of excitable cell.
The team found that the gene mutation prevents most KATP channels from binding with ankyrin, which typically acts as a cellular chaperone.
Functional diversity of ankyrin repeats in microbial proteins.
Role for the ankyrin eukaryotic-like genes of legioneila pneumophila in parasitism of protozoan hosts and human macrophages.