Ankyrins | definition of Ankyrins by Medical dictionary
ankyrin (redirected from Ankyrins)
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An erythrocyte membranal protein that binds spectrin. A deficiency in ankyrin may lead to a type of hereditary spherocytosis.
See also: nexins
[G. ankyra, anchor, + -in]
ankyrin /an·ky·rin/ (ang´kĭ-rin) a membrane protein of erythrocytes and brain that anchors spectrin to the plasma membrane at the sites of ion channels.
ankyrin Any of a family of proteins which mediate the binding of integral membrane proteins to the cytoskeleton, e.g., spectrin to the erythrocyte’s anion exchange (band-III) protein.
A structural protein in red blood cells that binds cell membrane transport molecules to spectrin.
References in periodicals archive
Role for the ankyrin eukaryotic-like genes of legioneila pneumophila in parasitism of protozoan hosts and human macrophages.
The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous.
Ankyrin repeat domain-encoding genes in the wPip strain of Wolbachia from the Cuiex jipiens group.
They found that the specific human gene mutation disrupts the ability of the protein ankyrin to regulate a key protein complex known as the KATP channel.
According to the researchers, a key finding in this study was identifying the ankyrin protein in the pancreatic beta cell, which is a type of excitable cell.
a genetic risk factor for psychiatric phenotypes?