ankyrin repeat


Also found in: Wikipedia.

ankyrin repeat

A short repetitive sequence of amino acids consisting of a beta strand followed by two alpha helices and a beta strand. The beta strands on adjacent ankyrin repeats combine to form a short antiparallel beta sheet. Ankyrin repeats were first identified in ankyrin, which tethers different proteins (e.g., nuclear and cytoplasmic proteins), helping regulate gene expression and embryonic development.
Mentioned in ?
References in periodicals archive ?
Two SNPs were located on a narrow region of chromosome 4 (from 15.59 Mb to 16.04 Mb), and the nearest genes were inhibitor of apoptosis protein 3 (IAP3) and sosondowah ankyrin repeat domain family member D (SOWAHD).
Genome wide association study on feed conversion ratio using imputed sequence data in chickens
However, it was proven that the SNP rs1800497 is a part of the exon 8 of ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1) gene [4].
DETERMINATION OF DOPAMINE RECEPTOR D2 GENE RS1800497 POLYMORPHISM USING REAL-TIME POLYMERASE CHAIN REACTION/DETERMINACIJA POLIMORFIZMA GENA ZA DOPAMINSKI RECEPTOR D2 RS1800497 PRIMENOM REAL-TIME POLIMERAZNE LANCANE REAKCIJE
DARPins (Designed Ankyrin Repeat Proteins) are artificial proteins that recognize and bind antigens.
Switzerland : Molecular Partners agrees partnership with Amgen
Several scaffolds, such as affibody molecules, knottins, designed ankyrin repeat proteins (DARPins), adnectins, and ADAPTs, have been preclinically evaluated for radionuclide molecular imaging and demonstrated capacity of imaging molecular targets in vivo at the day of injection [14].
Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors
Background: The Notch-regulated ankyrin repeat protein (NRARP) is recently found to promote proliferation of breast cancer cells.
Downregulation of Notch-regulated Ankyrin Repeat Protein Exerts Antitumor Activities against Growth of Thyroid Cancer
The active ingredient, which comprises several DARPins (designed ankyrin repeat proteins), is also easy to produce.
Treatment to cure breast cancer for good gets closer
The Z-disk proteins include [alpha]-actinin 2, cardiac ankyrin repeat protein, muscle LIM protein, LIM binding domain 3, myozenin 2, telethonin, and vinculin/metavinculin.
Sudden Cardiac Death: A Modern Pathology Approach to Hypertrophic Cardiomyopathy
The drug MP0112 is a designated ankyrin repeat protein that selectively binds VEGF-A isoforms.
Updates in the management of diabetic macular edema
"Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors," Journal of Virology 87(10): 5868-5881.
Recent publications
The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous.
Exploring symbioses by single-cell genomics
Biopharmaceutical company Cubist Pharmaceuticals Inc (NASDAQ:CBST) and Hydra Biosciences Inc announced on Tuesday the joint proposal to commence a Phase 1 clinical study for a small molecule antagonist of the human Transient Receptor Potential Ankyrin repeat 1 (TRPA1) ion channel.
Cubist Pharmaceuticals partners with Hydra Biosciences for Phase 1 clinical trial of TRPA1 Modulator for acute pain
EPH receptor A5, RAB17, SH3 and multiple ankyrin repeat domains 2, and GHRL are related to regulation of synapse assembly [32-34].
Analysis of cross-population differentiation between Thoroughbred and Jeju horses

Medical browser ?
Full browser ?