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When bones of a joint are fused, stiff, or rigid.
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Patient discussion about Ankylosing

Q. Is ankylosing spondylitis genetically inherited?

A. It is known today that ankylosing spondylitis (spondyloarthritis) has a very strong genetic connection. It is not a disease inhertited by a single gene that is dominant, but certainly there is genetic predisposition in families (and a more detailed information- about 90% of the patients express the HLA-B27 genotype).

Q. I have had ankylosing spondilitis for over 25 years. What is available at this point to mitigate the effects?

A. The mainstay of the treatment severe ankylosing spondylitis today are "anti-TNF", drugs that affect the immune system through blocking the action of a protein called TNF.

Other optional treatments include sulfasalazine and thalidomide.
Of course, all these treatments require prescription and consultation with a doctor (in this case usually rheumatologist).

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References in periodicals archive ?
Eli Lilly and Company (NYSE: LLY), a US-based pharmaceutical company, announced yesterday that the US Food and Drug Administration (FDA) has approved Taltz(R) (ixekizumab) injection 80mg/mL for the treatment of adults with active ankylosing spondylitis (AS), also known as radiographic axial spondyloarthritis (r-axSpA).
Food and Drug Administration (FDA) has approved Taltz (ixekizumab) injection 80 mg/mL for the treatment of adults with active ankylosing spondylitis (AS), also known as radiographic axial spondyloarthritis (r-axSpA).
The Ankylosing Spondylitis Disease Activity Scale (ASDAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), and Bath Ankylosing Spondylitis Metrology Index (BASMI) scores were calculated for all patients.
Ankylosing spondilitis, according to ASIF, is a "rheumatic inflammatory disease primarily affecting the spine and sacroiliac joints" (left and right joints found in the base of the spine that connects to the pelvic bone).
'Despite the seriousness of this disease, awareness of ankylosing spondylitis is very low.
Ankylosing spondylitis patients for whom full blood was available were selected from an existing disease registry for AS in Northern Norway.
He then discussed the ankylosing spondylitis classification criteria in patients who have already been diagnosed.
A.Z, a 20-year-old Hispanic female, presented to Bastyr University Clinic in San Diego seeking treatment for her diagnosis of ankylosing spondylitis.
New Delhi, [India] Nov 23 ( ANI ): Young adults in their late twenties and early thirties are experiencing a chronic condition called Ankylosing Spondylitis (AS).
Objective: Ankylosing Spondylitis (AS) is an inflammatory rheumatic disease that mainly affects the axial spine.
Recent studies have identified sensorineural hearing loss as a possible manifestation of ankylosing spondylitis.
Ankylosing Spondylitis (AS) is the most prevalent disease among the Spondylarthritis (SpAs) family.