selegiline

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selegiline

 [sĕ-lej´ĭ-lēn]
an agent used in treatment of parkinsonism; used as the hydrochloride salt in conjunction with levodopa and carbidopa.

selegiline

/se·le·gil·ine/ (sĕ-lej´ĭ-lēn) an antiparkinsonian agent used as the hydrochloride salt in conjunction with levodopa and carbidopa.

selegiline

(sə-lĕj′ə-lēn′)
n.
A selective monoamine oxidase inhibitor, C13H17N, used transdermally as an antidepressant and in its hydrochloride form in conjunction with levodopa and carbidopa to treat patients with Parkinson's disease.

deprenyl

Alternative pharmacology
A prescription drug used to treat Parkinson’s disease, which has acquired currency among some practitioners of alternative medicine as an anti-ageing substance; deprenyl acts on the substantia nigra., a region of the brain that is believed to age more rapidly than others, by blocking the degradation of dopaminergic neurotransmitters.

selegiline

l-Deprenyl Neuropharmacology A selective monoamine oxidase type B inhibitor which, with l-dopa, may be useful for early symptomatic treatment of parkinsonism

selegiline

A selective MONOAMINE OXIDASE INHIBITOR drug used in the treatment of PARKINSONISM. Selegiline is thought to retard the breakdown of DOPAMINE. Brand names are Eldepryl and Vivapril.

selegiline (seˑ·l·gi·lēnˈ),

n an MAO-B inhibitor used to treat Parkinson's disease. It also acts as an antioxidant and an immunostimulant, protects nerve tissue from degeneration, and has positive effects on cognition. Also called
deprenyl or
l-deprenyl.
References in periodicals archive ?
The drug Anipryl (also known as selegiline HCL or L-deprenyl), developed to treat Parkinson's disease in humans, was approved by the FDA in 1999 for use as a treatment for CCD.
Anipryl (selegiline, 1-deprenyl) is the only medication approved for use in dogs to treat CCD.
Amitraz, a monoamine oxidase inhibitor (MAOI), can also be dangerous when combined with certain other drugs, including antidepressants (such as those used to treat separation anxiety), Anipryl (used for canine cognitive dysfunction and Cushing's disease), and DL-Phenylalanine (DL PA), used to treat chronic pain in dogs.
According to Pfizer, which makes the drug, pet owners in studies reported that 69 percent to 75 percent of dogs improved in at least one clinical sign after one month of Anipryl therapy.
The agreement further provides for Ceva to pay the DRAXIS subsidiary a percentage royalty on European sales of Anipryl and/or the use of Anipryl(R) claims, in addition to nominal milestone payments upon the regulatory approval of Anipryl(R) in the U.
He was treated with Anipryl, which was not effective, and then switched to Lysodren (mitotane).
Amitraz can be dangerous when combined with antidepressants, such as Prozac (fluoxetine), or with other MAOl inhibitors, such as Anipryl (l-deprenyl, selegiline).
Like any drug, Anipryl can cause adverse reactions and side effects, and should not be used in combination with drugs that include, but not limited to, phenylpropanolamine, ephedrine, other tricyclic antidepressants (Clomicalm), amitraz (Mitaban dips or Preventic collars), fluoxetine, mirtazapine (a tetracyclic antidepressant used as an antiemetic and appetite stimulant, often in cancer patients), and tramadol.
It is safe to combine DLPA with all other arthritis drugs, but do not combine DLPA with MAOI drugs such as Anipryl (selegiline, l-deprenyl), used in the treatment of Cushing's Disease and canine cognitive dysfunction, or amitraz (found in tick collars).
Because of the long half-life of drugs such as fluoxetine (Prozac), you should wait at least five weeks after discontinuing use of SSRIs or TCAs before using Anipryl or amitraz.
Third quarter financial results were affected by a number of non-recurring production delays and lower than expected sales levels of Anipryl (R).