aminopterin
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aminopterin
Oncology A folic acid antagonist and inhibitor of dihydrofolate reductase; it is a potent cytotoxic agent fomerly used to manage leukemia; it has been replaced by MTX. See Methotrexate.aminopterin
(am-ĭ-nop′tĕr-ĭn)A folic acid antagonist used to treat acute leukemia.