ANGPTL3

(redirected from Angiopoietin-like protein 3)

ANGPTL3

A gene on chromosome 1p31.1-p22.3 that encodes angiopoietin-like protein 3, which is expressed primarily in the liver.

Molecular pathology
ANGPTL3 mutations are associated with familial hypobetalipoproteinaemia type 2.
References in periodicals archive ?
The product is an investigational monoclonal antibody to angiopoietin-like protein 3 (ANGPTL3).
The US FDA grants breakthrough therapy status to Regeneron Pharmaceuticals's evinacumab
The company said evinacumab is an investigational monoclonal antibody to angiopoietin-like protein 3 (ANGPTL3) that acts as an inhibitor of lipoprotein lipase and endothelial lipase and appears to play a central role in lipoprotein metabolism.
Regeneron passes US FDA breakthrough therapy designation for Evinacumab for Homozygous Familial Hypercholesterolemia (HoFH)
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