angiopoietin

(redirected from Angiopoietin-1)

angiopoietin

(an″jē-ō-poy-ē′tĭn; -poy′ĕ-tĭn) [ angio- + -poiet(ic) + -in]
Any of several genes (or the proteins they encode) that stimulate new blood vessel formation. The proteins encoded by angiopoietin are found in healthy cardiac endothelium and in diseased tissues such as arthritic joints and malignant tumors.
References in periodicals archive ?
AKB-9778 has demonstrated the ability to activate the Tie2 receptor irrespective of extracellular levels of its binding ligands, angiopoietin-1 (agonist) or angiopoietin-2 (antagonist).
Blocking miR-34a or injecting angiopoietin-1 in the mouse models improved their lung architecture by up to 90 percent, compared to controls.
Several growth factors are closely associated with blood vessel formation and remodeling, such as angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), and vascular endothelial growth factor (VEGF), [sup][1] each of which plays a different role in angiogenesis.
Conferone also precluded angiogenesis capability of treated HT-29 cells through an altered secretome profile, including vascular endothelial growth factor, Angiopoietin-1 and -2 factors.
Angiogenin, angiopoietin-1, angiopoietin-2, and endostatin serum levels in inflammatory bowel disease," Inflammatory Bowel Diseases, vol.
Kim, "Tacrolimus (FK506) inhibits interleukin-1[beta]-induced angiopoietin-1, Tie-2 receptor, and vascular endothelial growth factor through down-regulation of JNK and p38 pathway in human rheumatoid fibroblast-like synoviocytes," Joint Bone Spine, vol.
Relationship between gingival angiopoietin-1 concentrations and depth of the adjacent gingival sulcus.
Although significant changes in angiopoietin-1 (ANGPT1) mRNA expression were not observed between each condition, mRNA expression tended to be elevated in Pre and Post in Hypo Tr.
2007) Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.
High-level expression and purification of a designed angiopoietin-1 chimeric protein, COMP-Ang1, produced in Chinese hamster ovary cells.
74] suggested that angiopoietin-1 (Angl) may protect vascular endothelial cells from iopromide-induced apoptosis through PI 3-K and mTOR/S6 kinase, postulating that the pretreatment with Ang1 could help in maintaining normal vascular endothelial cell integrity before and during systemic RCM administration.
Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring.