angiogenin


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Related to angiogenin: VEGF

angiogenin

[an′jē·ōjen′in]
a protein that mediates the formation of blood vessels. A single-chain basic protein cloned from molecules of the tumor angiogenesis factor (TAF) in human colon cancer cells, angiogenin is used experimentally to stimulate the development of new blood vessels in wound healing, cerebrovascular accident, and coronary artery disease.

ANG

A gene on chromosome 14q11.1-q11.2 that encodes angiogenin, a potent mediator of angiogenesis, the structure of which is similar to pancreatic ribonuclease.
References in periodicals archive ?
Plasma angiogenin levels in acute coronary syndromes: implications for prognosis," European Heart Journal, vol.
Elevated angiogenin levels in chronic heart failure," Annals of Medicine, vol.
A pilot study of angiogenin in heart failure with preserved ejection fraction: a novel potential biomarker for diagnosis and prognosis?
Serum VEGF, bFGF and angiogenin levels were significantly elevated in patients with HCC (413.
It was concluded that high serum levels of VEGF, bFGF, angiogenin and endostatin were observed in patients with HCC.
70 Sensitivity, ng/L 10 1 k Angiogenin MIP-1 [beta] n 16/17 12/17 Average amount (SE) 9.
A surprising aspect of angiogenin is that its amino acid sequence has similarities to that of another human protein, an enzyme that breaks up RNA.
While Vallee kept his work on angiogenin under wraps, other scientists have described other blood-vessel stimulating chemicals.
The ancillary activity confuses the issue," he says, adding that angiogenin is 1,000 times as potent in triggering blood vessel growth as is the fibroblast growth factor.
For example, in addition to its angiogenic effects, angiogenin specifically degrades transfer RNA, but not messenger RNA (14).
Angiogenin is a cytotoxic, tRNA-specific ribonuclease in the RNase A superfamily.