Castleman's disease

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Any of a heterogeneous group of idiopathic, multicentric lymphoproliferative disorders primarily of young adults
Lab Increased IL-6 in serum and tissues, anemia, hypoalbuminemia, hypergammaglobulinemia
Management Anti-IL-6 antibodies
Therapy Surgical resection is the definitive therapy
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Castleman's disease

A heterogeneous group of idiopathic, multicentric lymphoproliferative disorders primarily of young adults Clinical Hepatosplenomegaly, lymphadenopathy Lab ↑ IL-6 in serum and tissues, anemia, hypoalbuminemia, hypergammaglobulinemia Management Surgical resection
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.