Introduction: Angelica dahurica Radix is the common herbal medicine with anti-cancer activities.
Materials and methods: We investigated the anti-cancer effects of Angelica dahurica extract in HT-29 colon cancer cell line.
Results and discussion: The organic extract of Angelica dahurica Radi decreased significantly the gene expression of p53, Bd, Bax and induced apoptosis via caspase cascade and cell cycle arrest.
Conclusions: This study has evaluated the ant-cancer activity of the organic extract of Angelica dahurica Radix against colon cancer cells and provided a basis of further development of the herbal extract for treatment of colon cancer.
Angelica dahurica Radix is the commonly used traditional herbal medicine in combination with other herbs for various antigens such as inflammation, liver dysfunction, infection and urinary disorders in China.
Angelicae Dahuricae Radix (ADR), the dried roots of Angelica dahurica (Fisch.
1) in rat plasma following oral administration of the extract of the roots of Angelica dahurica (Fisch.
Preparation of Angelica dahurica extract and the solutions for pharmacokinetic study
In vitro GABA-transaminase inhibitory compounds from the root of Angelica dahurica.