angel's trumpet(redirected from Angel's-trumpet)
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Datura ruaveolens, a flowering shrub native to the southeastern US. Portions of the plant are used for hallucinogenic effects. The flowers are made into a stew or tea, and the leaves are eaten. The flowers contain large quantities of the alkaloids atropine, hyoscyamine, and hyoscine. Ingestion of the plant produces intense thirst, visual disturbances, flushing, central nervous system hyperexcitability, sensory flooding, delirium, and paranoia. This is followed by hyperthermia, tachycardia, hypertension, visual hallucinations, disturbed consciousness, clonus, and subsequent convulsions. If the condition is untreated, death may occur.
Treatment consists of gastric lavage, followed by 1 to 4 mg of intravenous physostigmine sulfate. This dosage should reverse the acute delirious state in 1 to 2 hr, but it may need to be repeated several times.