angiopoietin

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angiopoietin

(an″jē-ō-poy-ē′tĭn; -poy′ĕ-tĭn) [ angio- + -poiet(ic) + -in]
Any of several genes (or the proteins they encode) that stimulate new blood vessel formation. The proteins encoded by angiopoietin are found in healthy cardiac endothelium and in diseased tissues such as arthritic joints and malignant tumors.
References in periodicals archive ?
The research findings described in this media release can be found in the scientific journal Nature Communications, under the title, "Reprogramming Mouse Fibroblasts into Engraftable Myeloerythroid and Lymphoid Progenitors" by Hui Cheng1,*, Heather Yin-Kuan Ang1,*, Chadi A EL Farran2,3, Pin Li1, Haitong Fang2, Tongming Liu1, Say Li Kong1, Michael Lingzi Chin1, Weiyin Ling1, Edwin Kok Hao Lim1, Hu Li4, Tara Huber1, Kyle M.
Patients with high levels of Ang1 and low levels of Tie2 were most likely to benefit from bevacizumab.
El factor soluble Ang1 estabiliza el endotelio, mientras que Ang2 aumenta la fuga capilar.
74] suggested that angiopoietin-1 (Angl) may protect vascular endothelial cells from iopromide-induced apoptosis through PI 3-K and mTOR/S6 kinase, postulating that the pretreatment with Ang1 could help in maintaining normal vascular endothelial cell integrity before and during systemic RCM administration.
Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1.
Gavin Thurston of the University of California, San Francisco and his colleagues genetically engineered mice to express higher-than-normal amounts of Ang1 or another protein, vascular endothelial growth factor (VEGF), which also promotes blood vessel growth.
The stance by Aruba has come about because authorities say the airline company owes the government about ANG1.
3] Ang1 is further cleaved by angiotensin-converting enzyme to form the octapeptide, angiotensin 2 (Ang2) (1).
The poor outcomes after stroke in type 1 diabetic rats have been attributed to HMGB1 mediated inflammatory response and Ang1 regulated angiogenesis [70, 71].
AMCI's AnyNET I/O family now includes: ANR2 LVDT/RVDT Signal Conditioner, ANA2 Resolver Interface, ANE2 SSI Interface, ANG1 Stepper Controller/Drive, etc.
Before Regeneron's discovery of the Angiopoietin family, of which Ang1 is a member, only one other family of growth factors specific for blood vessels had been defined and characterized.