angiopoietin

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angiopoietin

(an″jē-ō-poy-ē′tĭn; -poy′ĕ-tĭn) [ angio- + -poiet(ic) + -in]
Any of several genes (or the proteins they encode) that stimulate new blood vessel formation. The proteins encoded by angiopoietin are found in healthy cardiac endothelium and in diseased tissues such as arthritic joints and malignant tumors.
References in periodicals archive ?
Plasma angiopoietin-2 (ANG-2) is a proinflammatory cytokine that can regulate endothelial permeability [17].
Plasma concentrations of ANG-2, sE-selectin, IL-6, and IL-8 were measured by commercial ELISA kits (Cusabio, China) according to the manufacturer's instructions as follows: standards for ANG-2, sE-selectin, IL-6, and IL-8 were prepared for generating corresponding standard curves.
For the establishment of the model with the LIPS and ANG-2, the probability value (P value) was obtained from logistic regression analysis and then used as a new indicator for the diagnosis of ARDS based on receiver operating characteristic (ROC) curve analysis.
Prediction and Regression Analysis of LIPS, APACHE2 Score, and ANG-2, sE-Selectin, IL-6, and IL-8 Levels for ARDS
LIPS, APACHE2 Score, and ANG-2, sE-Selectin, IL-6, and IL-8 Concentration in the ARDS and Non-ARDS Groups.
Univariate analysis showed that ANG-2 level, sE-selectin level, APACHE2 score, LIPS, and septic shock were closely associated with ARDS (Table 4, univariate analysis).
Background: Angiopoietin-2 (Ang-2) plays a crucial role in hypoxia-induced angiogenesis and is expressed only in sites of vascular remodeling.
Several growth factors are closely associated with blood vessel formation and remodeling, such as angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), and vascular endothelial growth factor (VEGF), [sup][1] each of which plays a different role in angiogenesis.
[sup][11] Ang-2 plays a crucial role in this hypoxia-induced angiogenesis, and increased levels of Ang-2 concentrations can be detected in the peripheral blood of patients with CHD.
Given this information, we hypothesized that serum Ang-2 concentrations in patients with CHD might decrease after myocardial blood reperfusion by percutaneous coronary intervention (PCI) and the greater decreases in Ang-2 after PCI accompany more severe coronary artery stenosis.
Ang-2 concentrations in the blood samples were measured using enzyme-linked immunosorbent assay kits according to the manufacturer's instructions (RayBiotech, Inc., Norcross, GA, USA).
Pre-PCI serum Ang-2 concentrations in the study group were significantly higher than those in the control group (4625.06 [+ or -] 1838.06 vs.