androgen receptors

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androgen receptors

Molecules on the surface of cells that bind androgens and bring about their effects within the cells. They are specific GLYCOPROTEINS coded for by genes on the X chromosome.
References in periodicals archive ?
This tool is the first to measure the amount of androgen receptor protein present in a single cancer cell.
SUMO-1, human male germ cell development and the androgen receptor in the testis of men with normal and abnormal spermatogenesis," American Journal of Physiology.
Polymorphisms of the androgen receptor gene and the estrogen receptor beta gene are associated with androgen levels in women.
Jung-Mo Ahn and his colleagues at UT Southwestern Medical Center keyed in on blocking a critical docking point on the androgen receptor.
METHODS: The expression of androgen receptor and PSA were examined in LNCaP cells before and after treatment of isoflavones and/or curcumin.
1788) studied 96 adult men from the In CHIANTI study, a prospective population-based study of Italian adults, and examined in vivo expression of six estrogen receptor, estrogen-related receptor, and androgen receptor genes in peripheral blood leukocytes.
Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene.
The androgen receptor (AR) [3] plays a key role in prostate function and the development of prostate cancer (1-3).
Aberrant activation of the androgen receptor (AR) can result from gene amplification, mutation, phosphorylation, activation of coregulators, or androgen-independent activation.
In an article published April 9 in the advanced online edition of the journal Science, the scientists describe the development and testing of two novel compounds, MDV3100 and RD162, which block the androgen receptor (AR) in CRPC cells, and report results from clinical trials in which MDV3100 was found to lower prostate-specific antigen (PSA) levels--a marker for tumor growth--in men with CRPC.
Positivity to PAS and Alcyan blue reactions and androgen receptor immunolocalization was evaluated with a semiquantitative system (0, 1, 2 or 3 crosses) in JG, ventral Bowman glands (VBG), dorsal Bowman glands (DBG), sensitive chemoreceptory neuroepithelium (Ne), receptor-free epithelium (RFE) and nasal septum respiratory epithelium (RE) histological slides of male rats at 5, 15, 25 and 35 days of age.

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