scaffold protein

(redirected from Anchoring Protein)
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A multivalent protein that coordinates the location of enzymes in close proximity to specific substrates. Scaffold proteins are structurally and functionally linked to macromolecule assembly, and follow ordered pathways, accomplished by switching proteins through discrete conformations as they’re incorporated into a growing molecular complex

scaffold protein

(skaf′ōld″)
A protein that links other proteins so they can jointly perform some biochemical function.
References in periodicals archive ?
The developmental GluN2B-to-GluN2A subunit switch alters a number of NMDAR properties including affinity for glutamate, small molecules (phenylethanolamines, PEAs), and ions (protons, zinc); channel open probability and deactivation rates; the presence or absence of activity-dependent synaptic integration; and subunit-selective interactions with intracellular signaling and anchoring proteins (Fig.
Epidermolysis Bullosa (EB) is a heterogeneous group of diseases characterized by a genetic defect of the anchoring proteins between the epidermis and the dermis and can be inherited either autosomal recessively or autosomal dominant.
Schneewind, "Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria," Microbiology and Molecular Biology Reviews, vol.
In this project we aim to investigate the effect of mechanical forces in the anchoring proteins and its role during attachment.
There is mounting evidence that regulation of actinmembrane anchoring by lipids and dedicated anchoring proteins is critical for the formation of dynamic actin structures needed for essential functions such as cell division, migration, and mechanosensing.