scaffold protein

(redirected from Anchoring Protein)
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A multivalent protein that coordinates the location of enzymes in close proximity to specific substrates. Scaffold proteins are structurally and functionally linked to macromolecule assembly, and follow ordered pathways, accomplished by switching proteins through discrete conformations as they’re incorporated into a growing molecular complex

scaffold protein

(skaf′ōld″)
A protein that links other proteins so they can jointly perform some biochemical function.
References in periodicals archive ?
An ABc mutant NMDAR would be expected to mimic overexpression of GluN2A at immature synapses, due to the non-specificity of the predominating PSD anchoring protein, SAP102, for GluN2A or G1uN2B.
Due to postnatal modifications in the types of anchoring proteins that occupy the PSD, this slot and peg phenomenon has important ramifications for developmental regulation of synaptic NMDAR composition as well as proteomic analysis of NMDAR molecular complexes (Husi et at.
Epidermolysis Bullosa (EB) is a heterogeneous group of diseases characterized by a genetic defect of the anchoring proteins between the epidermis and the dermis and can be inherited either autosomal recessively or autosomal dominant.
There is mounting evidence that regulation of actinmembrane anchoring by lipids and dedicated anchoring proteins is critical for the formation of dynamic actin structures needed for essential functions such as cell division, migration, and mechanosensing.