amyloid angiopathy


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am·y·loid an·gi·op·a·thy

deposition of acellular hyaline material in small arteries and arterioles of the leptomeninges and cerebral cortex in the elderly with resulting predilection for recurrent lobar intraparenchymal hematomas.

amyloid angiopathy

An abnormality of cerebral blood vessels in which amyloid is deposited in the walls of small arteries and arterioles. It may occur in those with chronic infectious and inflammatory disorders or B-cell lymphoma and is a common contributor to intracerebral hemorrhage or Alzheimer's disease in the elderly.
See also: angiopathy
References in periodicals archive ?
EXAMPLE 4, SAMPLE AUTOPSY SIGNOUT: * Frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP), Type A, with: *** Severe temporal lobe atrophy, bilateral *** Frontal lobe atrophy, mild *** Hippocampal sclerosis, bilateral, severe *** Neuronal intranuclear ("lentiform") inclusions * Alzheimer disease neuropathology changes, "high", (A2,B3,C1): *** Thal phase for amyloid plaques: 3 (A2) *** Braak and Braak neurofibrillary stage: V (B3) *** CERAD neuritic plaque score: Predominantly sparse (CI) *** No cerebral amyloid angiopathy is identified * No Lewy body disease pathology is identified Comment: FTLD-TDP, Type A, is identified with associated severe TDP-43 proteinopathy, circumscribed atrophy of bilateral anteromedial temporal lobes and bilateral hippocampal sclerosis.
MR Spectroscopy in the Diagnosis of Cerebral Amyloid Angiopathy Presenting as a Brain Tumor.
Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study.
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy," Brain, vol.
Links between cerebral amyloid angiopathy, dementia, and brain aging will continue to shed light on the development of dementia and raise anew the question of the role of cerebral hypoperfusion in Alzheimer's disease.
Approximately 25% of cognitively normal older adults and nearly 50% of people older than 80 years also show beta-amyloid on PET scans, as do patients with conditions such as dementia with Lewy bodies and cerebral amyloid angiopathy.
Q My elderly cousin was recently diagnosed with cerebral amyloid angiopathy.
This regional association with dementia subtypes is consistent with the hypothesis that lobar cerebral microbleeds reflect cerebral amyloid angiopathy, which is consistent with Alzheimer's disease, while those in deep areas reflect hypertensive arteriopathy, which is important in vascular dementia," Lenore Launer, Ph.
Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy.
The patient was elderly; however, no foci of prior hemorrhage were noted, which argued against cerebral amyloid angiopathy.
Physicians at Hadassah University Hospital, Ein Karem knew during Prime Minister Ariel Sharon's first hospitalization in December that he suffered from cerebral amyloid angiopathy (CAA), a disease of the blood vessels in the brain, a medical source told Ha'aretz on Tuesday.