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Related to aminophenazone: amidopyrine


Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds; may cause leukocytopenia; used to measure total body water.
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The current research was aimed to synthesize sulfonamide derivatives aminophenazone and to evaluate their biological potential.
This method is based on the same reaction sequence as the Creatinine-PAP (phenol aminophenazone) method (29) consisting of 4 consecutive enzymatic steps via creatininase, creatinase, sarcosine oxidase, and peroxidase, but using a different chromophore (2,4,6-triiodo-3-hydroxybenzoic acid) and a modified detergent composition.