aminoacyl-tRNA synthetase


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aminoacyl-tRNA synthetase

Any of a class of enzymes (e.g., phenylalanyl-tRNA synthetase) that charge tRNAs with a cognate amino acid.

aminoacyl-tRNA synthetase

One of a group of 20 enzymes each of which is specific for the catalyzation of the linkage of a particular AMINO ACID to its own type of TRANSFER RNA during protein synthesis. There are 20 amino acids in body proteins.
References in periodicals archive ?
Rodriguez performed many laborious experiments in which she removed portions of the aminoacyl-tRNA synthetase that interact with the anticodon stem of the transfer RNA, far from the part of the enzyme that binds the amino acid.
In all, Rodriguez found that separately removing seven different "gears" from a distant part of the molecule each caused the amino acid to bind more tightly to the aminoacyl-tRNA synthetase.
To illustrate the power of matching against secondary structure predictions, we present a novel proposed protein alignment, found using this system, for the protein class of aminoacyl-tRNA synthetases.
The aminoacyl-tRNA synthetases help establish the rules of the genetic code, by mediating the translation of DNA to protein.
Therefore, an RNA-only-based protein synthesis system would require a set of RNA molecules capable of synthesizing aminoacyl-RNAs, which are produced by the protein aminoacyl-tRNA synthetases in extant biology.
The correct amino acid is attached to each tRNA species by specific enzymes called aminoacyl-tRNA synthetases.
9:30 INVESTIGATING TRNA CHANNELING BY AMINOACYL-TRNA SYNTHETASES AND ELONGATION FACTOR TU
In these 36 reports, contributors describe their most recent research in aminoacyl-tRNA synthetases, the point in gene expression in which the genetic code is first defined.
Furthermore, the full complement of aminoacyl-tRNAs necessary for translation is not entirely formed by the aminoacyl-tRNA synthetases (AARS).
Antibacterial activity will be achieved through inhibition of essential aminoacyl-tRNA synthetases (RS).
11:00 Size Identification of Aminoacyl-tRNA Synthetases from Plants
The existence of a complex of aminoacyl-tRNA synthetases in plants is still in question.