aminoacyl-tRNA synthetase


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aminoacyl-tRNA synthetase

Any of a class of enzymes (e.g., phenylalanyl-tRNA synthetase) that charge tRNAs with a cognate amino acid.

aminoacyl-tRNA synthetase

One of a group of 20 enzymes each of which is specific for the catalyzation of the linkage of a particular AMINO ACID to its own type of TRANSFER RNA during protein synthesis. There are 20 amino acids in body proteins.
References in periodicals archive ?
T Wong, "Congruence of evidence for a Methanopyrus-proximal root of life based on transfer RNA and aminoacyl-tRNA synthetase genes," Gene, vol.
Rodriguez performed many laborious experiments in which she removed portions of the aminoacyl-tRNA synthetase that interact with the anticodon stem of the transfer RNA, far from the part of the enzyme that binds the amino acid.
(24)] Miscellaneous Aminoacyl-tRNA synthetase autoantibodies [Park et al.
To illustrate the power of matching against secondary structure predictions, we present a novel proposed protein alignment, found using this system, for the protein class of aminoacyl-tRNA synthetases. The proposed alignment agrees with the few existing alignments based on primary sequence similarities (or homologies) where such are known, and predicts novel alignments for some enzymes having no known primary sequence similarities.
Therefore, an RNA-only-based protein synthesis system would require a set of RNA molecules capable of synthesizing aminoacyl-RNAs, which are produced by the protein aminoacyl-tRNA synthetases in extant biology.
Partnering with these 20 tRNAs are 20 matching helper enzymes known as synthetases (aminoacyl-tRNA synthetases), whose job it is to load their partner tRNAs with the correct amino acid.
Interstitial lung disease with autoantibodies against aminoacyl-tRNA synthetases in the absence of clinically apparent myositis.
Called aminoacyl-tRNA synthetases (aaRSs), they link amino acids to RNA strings, playing an important role in the essential life process of converting genes into proteins.
The correct amino acid is attached to each tRNA species by specific enzymes called aminoacyl-tRNA synthetases.
9:30 INVESTIGATING TRNA CHANNELING BY AMINOACYL-TRNA SYNTHETASES AND ELONGATION FACTOR TU
In these 36 reports, contributors describe their most recent research in aminoacyl-tRNA synthetases, the point in gene expression in which the genetic code is first defined.
Furthermore, the full complement of aminoacyl-tRNAs necessary for translation is not entirely formed by the aminoacyl-tRNA synthetases (AARS).