Of note, semicarbazide used for reference blockade in our assays is no more the best SSAO inhibitor available to date; SSAO has even been renamed primary amine oxidase to signify that it is better defined by its substrates (endogenous or exogenous) rather than by its inhibitor(s) .
Nevertheless, our comparative study clearly indicated that none of the tested phenolic compounds directly inhibited primary amine oxidase, also named SSAO/VAP-1.
Jalkanen, "A cell surface amine oxidase directly controls lymphocyte migration," Immunity, vol.
Shevchenko, Thermostable AY- cyclodextrin conjugates of two similar plant amine oxidases
and their properties, Biotechnol.
The enzymes used in their work include amino acid-lyases, (48)-(57) aromatic amino acid decarboxylases, (58)-(64) and amine oxidases
TYRP1, Tyrosinase-related protein 1 Group 3: Copper amine oxidase
The aim of the present study was to extract and purify amine oxidase from pea seedlings, to determine the activity and selectivity of the purified enzyme towards different amine substrates with a Clark-type oxygen sensor, and to examine the possible application of the enzyme as a bioselective element in amine biosensors.
The amine oxidase preparation was stable at -18[degrees]C and there was no detectable loss of activity in 6 months at this temperature.
This parameter A was used for the characterization of amine oxidase activity.
Instead, TOPA turned out to be a built-in partner, which the cell fashions (after the amine oxidase
is made) by modifying one of the enzyme's component amino acids.
The molecular weight of pea seedlings amine oxidase (PSAO) has been found to be between 150 and 180 kDa [2, 7].
Amine oxidase catalyses the oxidative deamination of amines to the corresponding aldehyde, ammonia, and hydrogen peroxide [8, 11]: