amiloride


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Related to amiloride: furosemide, Amiloride hydrochloride

amiloride

 [ah-mil´o-rīd]
a potassium sparing diuretic, used as the hydrochloride salt, usually in combination with hydrochlorothiazide, in the treatment of edema and hypertension and the prevention and treatment of hypokalemia.

amiloride

/amil·o·ride/ (ah-mil´ah-rīd) a potassium-sparing diuretic used as the hydrochloride salt in the treatment of edema and hypertension and in the prevention and treatment of hypokalemia.

amiloride

Nephrology A drug that blocks the Na+/H+ antiporter, used clinically as a potassium-sparing diuretic. See Diuretics, Potassium-sparing diuretic Pulmonology An aerosolized sodium channel blocker that may slow the progression of pulmonary dysfunction in cystic fibrosis. See Diuretics, Potassium-sparing diuretic.

amiloride

A thiazide DIURETIC drug that acts by reducing reabsorption of sodium, and thus water, in the kidneys. A potassium-sparing diuretic used in the treatment of high blood pressure (HYPERTENSION), HEART FAILURE or other conditions in which excess fluid is retained in the body. The drug is on the WHO official list. Formulated in combination with other drugs under brand names such as Amil-Co, Burinex A, Fru-Co, Frumil, Kalten, Lasoride, Moducren, Moduret 25, Moduretic and Navispare.

amiloride

a potassium-sparing diuretic.
References in periodicals archive ?
Amiloride was administered 45 min before, and aspirin was administered 1 h before the nociceptive stimulus which was 0.
sup][43] An increased volume of the bladder, resulting in an augment of the hydrostatic pressure of endothelia of bladder, could induce improved inward whole-cell current which is partly abolished by amiloride.
The combination of amiloride and KCl has been successfully used in the past (3).
Further, based on our experience, the use of amiloride during pregnancy was not associated with any adverse effects on the mother or the fetus.
Interestingly, the inhibitory effect of high salt on NO production was significantly restored by amiloride in HUVECs (Figures 3(c) and 3(d)).
But the PATHWAY-3 trial demonstrates that, with the half-dose combination approach, amiloride cancels those side effects, while hydrochlorothiazide (HCTZ) neutralizes amiloride's tendency to boost serum potassium, he explained.
7 mm Hg with amiloride monotherapy, by 14 mm Hg with HCTZ, and by 17.
Attenuation of pulmonary arterial smooth muscle cell proliferation following hypoxic pulmonary hypertension by the Na+/H+ exchange inhibitor amiloride.
11) In addition to sodium restriction, patients with grade 2 ascites (moderate ascites with proportionate abdominal distension) should receive a low-dose diuretic, such as spironolactone (initial dose, 50-100 mg/d; increase up to 200-300 mg/d) (13) or amiloride (5-10 mg/d).
The gene responsible for synthesizing DAO is amiloride binding protein 1 (ABP1), also known as amine oxidase, copper containing 1 (A0C1).
The samples contained amiloride and hydrochlorothiazide, which are both prohibited as diuretics and masking agents.