amide

(redirected from Amidation)
Also found in: Dictionary, Thesaurus, Encyclopedia.

amide

 [am´īd]
any compound derived from ammonia by substitution of an acyl radical for hydrogen, or from an acid by replacing the -OH group by -NH2.

am·ide

, primary amidesecondary amidetertiary amide (am'īd, am'id),
A substance derived from ammonia by replacing hydrogen atoms with acyl groups, R-CO-NH2. Replacement of one hydrogen atom results in formation of a primary amide; of two hydrogen atoms, a secondary amide; and of three hdyrogen atoms, a tertiary amide. Amides can also be derived from a carboxylic acid by replacing a carboxylic OH with NH2 from a carboxylic acid by replacement of a carboxylic OH by NH2. Replacement of one hydrogen atom constitutes a primary amide; that of two hydrogen atoms, a secondary amide; and that of three atoms, a tertiary amide.

amide

(ăm′īd′, -ĭd)
n.
1. An organic compound, such as acetamide, containing the CONH2 group.
2. The anion of ammonia, NH2- or a compound containing this anion, such as sodium amide, NaNH2.

a·mid′ic (ə-mĭd′ĭk, ă-mĭd′-) adj.

am·ide

(am'īd)
A substance formally derived from ammonia through the substitution of one or more of the hydrogen atoms by acyl groups, R-CO-NH2, or from a carboxylic acid by replacement of a carboxylic OH by NH2. Replacement of one hydrogen atom constitutes a primary amide; that of two hydrogen atoms, a secondary amide; and that of three atoms, a tertiary amide.

amide

a compound formed from ammonia in which one or more hydrogen atoms are replaced by a metal or acid radical.

am·ide

(am'īd)
A substance formally derived from ammonia through the substitution of one or more of the hydrogen atoms by acyl groups, R-CO-NH2, or from a carboxylic acid by replacement of a carboxylic OH by NH2.
References in periodicals archive ?
1 (curve 1), Table 2) that in case of vegetable oil amidation it is possible to receive mainly the amides of fatty acids (AFA) at temperatures of 90.100[degrees]C.
It is well known that vitamin C besides acting as a strong antioxidant also functions as a co-factor of an enzyme peptidylglycine a-amidating monooxygenase (PAM), which is responsible for amidation of various neuropeptides (Eipper et al., 1993).
Both NmU and NmS share the 7 residues located in the C terminus of their sequence, including the amidation of the C-terminal amino acid.
Amidation of the C-terminus is a multistep process.
This consisted of an N-terminal putative signal peptide, an acidic amino acid residue-rich spacer peptide domain, a single copy of a mature AcT-2 sequence, and a C-terminal processing and amidation site (Figure 2(c)).
immobilized biomolecule, bovine serum albumin (BSA) protein via two-step process of diimide-activated amidation on MWCTs.
This could be overcome by expression of AMP encoding gene directly into the tumour cells or by replacement of peptide amino acids by their D-amino acids and modification of peptide terminal by amidation [117].
The in situ amidation of aqueous ammonia NMSO upon curing was only evident among the trisubstituted soybean oil triglycerides (230 mg KOH/g), and not MSO-2 (156 mg KOH/g).
It seems to be retractable to increase resistance of these peptide drugs by modification (acetylation and amidation) of N and C-terminus of the peptides respectively replacement of the amino acids at the predicted cleavage sites with D-amino acids, this mode of designing and modification of peptide have shown to improve stability of a recently discovered glucagon like peptide GLP-1-(7-34)-amide It has been developed as a treatment for Type II diabetes.
In addition to phosphorylation and ubiquitination, proteins can undergo additional modifications via methylation, acetylation, glycosylation, oxidation, sulfation, hydroxylation, nitrosylation, amidation, etc.
Reactions include amidation and 1,3-dipolar cycloaddition.
Several technologies are available to manufacture biodiesel, such as transesterification, amidation with diethylamine, catalyzing pyrolysis, and transesterification in supercritical methanol.